LncRNA BACE1-AS delays the propagation of Cryptosporidium parvum through regulating cell apoptosis by targeting the miR-6805-5p/IRF3 axis

LncRNA BACE1-AS delays the propagation of Cryptosporidium parvum through regulating cell apoptosis by targeting the miR-6805-5p/IRF3 axis

ABSTRACT Cryptosporidium spp. are important zoonotic pathogens causing diarrhea in humans and various animals. To date, there are still no effective drugs and vaccines for the prevention and treatment of cryptosporidiosis, mainly due to the absence of knowledge on the interaction mechanisms between...

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Bibliographic Details
Main Authors: Shuang Huang, Xin Yang, Ting-Li Liu, Gui-Rong Hu, Qian Yao, Jun-Ke Song, Ying-Ying Fan, Guang-Hui Zhao
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:Microbiology Spectrum
Subjects:
Cryptosporidium parvum
BACE1-AS
miR-6805-5p
IRF3
apoptosis
propagation
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02022-24
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