The association of hyperthyroidism and immune thrombocytopenia: Are we still missing something?

Though the American society of hematology Guidelines and British guidelines do not recommend screening of thyroid diseases in cases of immune thrombocytopenia (ITP), more than 160 cases of hyperthyroidism associated with ITP have been reported. Numerous case reports would suggest that patients with...

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Main Author: Kalyan Mansukhbhai Shekhda
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Tzu Chi Medical Journal
Subjects:
Online Access:http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2018;volume=30;issue=3;spage=188;epage=190;aulast=Shekhda
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author Kalyan Mansukhbhai Shekhda
author_facet Kalyan Mansukhbhai Shekhda
author_sort Kalyan Mansukhbhai Shekhda
collection DOAJ
description Though the American society of hematology Guidelines and British guidelines do not recommend screening of thyroid diseases in cases of immune thrombocytopenia (ITP), more than 160 cases of hyperthyroidism associated with ITP have been reported. Numerous case reports would suggest that patients with ITP and concurrent hyperthyroidism would respond to control of thyroid disease rather than the standard ITP treatment. Although this issue is still debatable, we report a case of a young female with a previous diagnosis of hyperthyroidism which was not well controlled, had presented with severe thrombocytopenia. Initially, all work-up had been done to find out the cause of thrombocytopenia. After all normal reports except deranged thyroid function tests, the patient was labeled as ITP and started on steroids. Even after a few months of steroid treatment, platelet counts had not improved. However, after starting antithyroid drugs, platelet counts had become normalized.
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spelling doaj-art-8b5531b6d629470db20bb38ffeebfc652025-08-20T03:49:17ZengWolters Kluwer Medknow PublicationsTzu Chi Medical Journal1016-31902223-89562018-01-0130318819010.4103/tcmj.tcmj_139_17The association of hyperthyroidism and immune thrombocytopenia: Are we still missing something?Kalyan Mansukhbhai ShekhdaThough the American society of hematology Guidelines and British guidelines do not recommend screening of thyroid diseases in cases of immune thrombocytopenia (ITP), more than 160 cases of hyperthyroidism associated with ITP have been reported. Numerous case reports would suggest that patients with ITP and concurrent hyperthyroidism would respond to control of thyroid disease rather than the standard ITP treatment. Although this issue is still debatable, we report a case of a young female with a previous diagnosis of hyperthyroidism which was not well controlled, had presented with severe thrombocytopenia. Initially, all work-up had been done to find out the cause of thrombocytopenia. After all normal reports except deranged thyroid function tests, the patient was labeled as ITP and started on steroids. Even after a few months of steroid treatment, platelet counts had not improved. However, after starting antithyroid drugs, platelet counts had become normalized.http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2018;volume=30;issue=3;spage=188;epage=190;aulast=ShekhdaAntithyroid drugsAutoimmune diseasePlatelet countsSteroids
spellingShingle Kalyan Mansukhbhai Shekhda
The association of hyperthyroidism and immune thrombocytopenia: Are we still missing something?
Tzu Chi Medical Journal
Antithyroid drugs
Autoimmune disease
Platelet counts
Steroids
title The association of hyperthyroidism and immune thrombocytopenia: Are we still missing something?
title_full The association of hyperthyroidism and immune thrombocytopenia: Are we still missing something?
title_fullStr The association of hyperthyroidism and immune thrombocytopenia: Are we still missing something?
title_full_unstemmed The association of hyperthyroidism and immune thrombocytopenia: Are we still missing something?
title_short The association of hyperthyroidism and immune thrombocytopenia: Are we still missing something?
title_sort association of hyperthyroidism and immune thrombocytopenia are we still missing something
topic Antithyroid drugs
Autoimmune disease
Platelet counts
Steroids
url http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2018;volume=30;issue=3;spage=188;epage=190;aulast=Shekhda
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