Regulation of type 3 fimbria expression by RstA affects biofilm formation and virulence in Klebsiella pneumoniae ATCC43816

Regulation of type 3 fimbria expression by RstA affects biofilm formation and virulence in Klebsiella pneumoniae ATCC43816

ABSTRACT Klebsiella pneumoniae causes both community-acquired and healthcare-associated infections, presenting a major therapeutic challenge to global public health. RstBA is a common two-component regulatory system that controls downstream gene expression in certain Enterobacteriaceae species. Howe...

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Bibliographic Details
Main Authors: Xiaoyun Zhang, Yaxuan Zhai, Jie Zhu, Zhichen Zhu, Yicheng Wen, Qizhao Gao, Liang Wang, Jiayao Lin, Yan Qian, Liang Chen, Hong Du
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:Microbiology Spectrum
Subjects:
Klebsiella pneumoniae
RstA
type 3 fimbriae
biofilm formation
virulence
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03076-24
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