Case Report: A case of transcatheter aortic valve replacement in a patient with a small aortic annulus using the Acurate Neo2
Small aortic annulus poses a major challenge in aortic valve replacement due to the increased risk of prosthesis–patient mismatch (PPM) and increased surgical risk. In recent years, transcatheter aortic valve replacement (TAVR) has emerged as a popular alternative to the traditional surgical aortic...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1513802/full |
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| author | Shahzil Abdur Rehman Malik Jamshed Ali Maleeha Javed Kamran Hussain Navaira Azeem Nasir Rehman Osman Faheem |
| author_facet | Shahzil Abdur Rehman Malik Jamshed Ali Maleeha Javed Kamran Hussain Navaira Azeem Nasir Rehman Osman Faheem |
| author_sort | Shahzil Abdur Rehman Malik |
| collection | DOAJ |
| description | Small aortic annulus poses a major challenge in aortic valve replacement due to the increased risk of prosthesis–patient mismatch (PPM) and increased surgical risk. In recent years, transcatheter aortic valve replacement (TAVR) has emerged as a popular alternative to the traditional surgical aortic valve replacement. We present the case of an 80-year-old woman with a small aortic annulus who underwent TAVR using a self-expanding transcatheter heart valve Acurate Neo2 after an non-ST-segment elevation myocardial infarction (NSTEMI) presentation. These risks, combined with advanced age, significant co-morbidities, and a severely calcified small aortic annulus, supported the choice of TAVR with a self-expanding Acurate Neo2 valve. Despite multiple risk factors for PPM, the patient had a successful outcome without major complications. Our case highlights the off-label use of the Acurate Neo2 valve in one of the smallest aortic annuli reported to date, showcasing its feasibility in Asian and resource-limited settings. |
| format | Article |
| id | doaj-art-8b34173cf04f4195a17a44f25cb963cd |
| institution | Kabale University |
| issn | 2297-055X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj-art-8b34173cf04f4195a17a44f25cb963cd2025-02-06T07:10:12ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-02-011210.3389/fcvm.2025.15138021513802Case Report: A case of transcatheter aortic valve replacement in a patient with a small aortic annulus using the Acurate Neo2Shahzil Abdur Rehman Malik0Jamshed Ali1Maleeha Javed2Kamran Hussain3Navaira Azeem4Nasir Rehman5Osman Faheem6Medical College, Aga Khan University, Karachi, PakistanSection of Cardiology, Department of Medicine, Aga Khan University, Karachi, PakistanSection of Cardiology, Department of Medicine, Aga Khan University, Karachi, PakistanSection of Cardiology, Department of Medicine, Aga Khan University, Karachi, PakistanSection of Cardiology, Department of Medicine, Aga Khan University, Karachi, PakistanSection of Cardiology, Department of Medicine, Aga Khan University, Karachi, PakistanSection of Cardiology, Department of Medicine, Aga Khan University, Karachi, PakistanSmall aortic annulus poses a major challenge in aortic valve replacement due to the increased risk of prosthesis–patient mismatch (PPM) and increased surgical risk. In recent years, transcatheter aortic valve replacement (TAVR) has emerged as a popular alternative to the traditional surgical aortic valve replacement. We present the case of an 80-year-old woman with a small aortic annulus who underwent TAVR using a self-expanding transcatheter heart valve Acurate Neo2 after an non-ST-segment elevation myocardial infarction (NSTEMI) presentation. These risks, combined with advanced age, significant co-morbidities, and a severely calcified small aortic annulus, supported the choice of TAVR with a self-expanding Acurate Neo2 valve. Despite multiple risk factors for PPM, the patient had a successful outcome without major complications. Our case highlights the off-label use of the Acurate Neo2 valve in one of the smallest aortic annuli reported to date, showcasing its feasibility in Asian and resource-limited settings.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1513802/fullself-expanding transcatheter heart valvesprosthesis-patient mismatchsmall aortic annulusresource limited settingscase report |
| spellingShingle | Shahzil Abdur Rehman Malik Jamshed Ali Maleeha Javed Kamran Hussain Navaira Azeem Nasir Rehman Osman Faheem Case Report: A case of transcatheter aortic valve replacement in a patient with a small aortic annulus using the Acurate Neo2 Frontiers in Cardiovascular Medicine self-expanding transcatheter heart valves prosthesis-patient mismatch small aortic annulus resource limited settings case report |
| title | Case Report: A case of transcatheter aortic valve replacement in a patient with a small aortic annulus using the Acurate Neo2 |
| title_full | Case Report: A case of transcatheter aortic valve replacement in a patient with a small aortic annulus using the Acurate Neo2 |
| title_fullStr | Case Report: A case of transcatheter aortic valve replacement in a patient with a small aortic annulus using the Acurate Neo2 |
| title_full_unstemmed | Case Report: A case of transcatheter aortic valve replacement in a patient with a small aortic annulus using the Acurate Neo2 |
| title_short | Case Report: A case of transcatheter aortic valve replacement in a patient with a small aortic annulus using the Acurate Neo2 |
| title_sort | case report a case of transcatheter aortic valve replacement in a patient with a small aortic annulus using the acurate neo2 |
| topic | self-expanding transcatheter heart valves prosthesis-patient mismatch small aortic annulus resource limited settings case report |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1513802/full |
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