Association of Malnutrition in Patients Admitted with Complete Heart Block: A Nationwide Analysis
Background: Complete heart block (CHB) is a cardiac conduction disorder that can be fatal if not treated promptly. Malnutrition has been shown to have a significant impact on various cardiac conditions. Aim: The objective was to determine if the nutritional status influences the outcomes in patients...
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MDPI AG
2025-03-01
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| author | Nahush Bansal Sonaal Singla Jasneet Kaur Nikita Sharma Feehaan Sultan Shuhao Qiu |
| author_facet | Nahush Bansal Sonaal Singla Jasneet Kaur Nikita Sharma Feehaan Sultan Shuhao Qiu |
| author_sort | Nahush Bansal |
| collection | DOAJ |
| description | Background: Complete heart block (CHB) is a cardiac conduction disorder that can be fatal if not treated promptly. Malnutrition has been shown to have a significant impact on various cardiac conditions. Aim: The objective was to determine if the nutritional status influences the outcomes in patients with CHB. Methods: A retrospective study was conducted using the United States Inpatient Sample database on patients admitted with complete heart block. Outcomes were compared between the patients with and without concomitant malnutrition. Results: The study included 37,480 patients with complete heart block, of whom 603 (1.61%) had malnutrition. Compared to patients without malnutrition, patients with malnutrition had higher adjusted in-hospital mortality rates (aOR 2.61; 95% CI 1.46–3.48), longer length of stay (LOS) (mean increase 2.23 days; <i>p</i> < 0.01), and higher hospital charges (mean increase USD 76,907.32; <i>p</i> < 0.01). The malnourished group also had significantly higher rates of cardiogenic shock (aOR 2.80; 95% CI 1.56–5.03; <i>p</i> < 0.01) and acute respiratory failure (aOR 2.65; 95% CI 1.67–4.22; <i>p</i> < 0.01). Patients with malnutrition had significantly lower rates of permanent pacemaker (aOR 0.57; 95% CI 0.38–0.86; <i>p</i> < 0.01) and longer delay to permanent pacemaker intervention (mean increase 1.38 days; <i>p</i> = 0.014). The impact on outcomes was worse in patients with severe malnutrition compared to those with mild to moderate malnutrition. Conclusions: Malnutrition is associated with significantly worse outcomes in CHB admissions, including higher mortality, resource utilization, complications, and lower and delayed pacemaker intervention. Individualized and timely nutritional interventions might potentially play a key role in improving outcomes in these patients. |
| format | Article |
| id | doaj-art-8b314c361ea84f998095865bb1509314 |
| institution | OA Journals |
| issn | 2673-4168 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Obesities |
| spelling | doaj-art-8b314c361ea84f998095865bb15093142025-08-20T01:48:45ZengMDPI AGObesities2673-41682025-03-01511810.3390/obesities5010018Association of Malnutrition in Patients Admitted with Complete Heart Block: A Nationwide AnalysisNahush Bansal0Sonaal Singla1Jasneet Kaur2Nikita Sharma3Feehaan Sultan4Shuhao Qiu5Department of Internal Medicine, University of Toledo, Toledo, OH 43606, USADepartment of Internal Medicine, University of California, Riverside, CA 92521, USADepartment of Internal Medicine, Nassau University Medical Center, New York, NY 11554, USADivision of Cardiology, Dayanand Medical College, Ludhiana 141001, IndiaDepartment of Internal Medicine, University of Toledo, Toledo, OH 43606, USADepartment of Internal Medicine, University of Toledo, Toledo, OH 43606, USABackground: Complete heart block (CHB) is a cardiac conduction disorder that can be fatal if not treated promptly. Malnutrition has been shown to have a significant impact on various cardiac conditions. Aim: The objective was to determine if the nutritional status influences the outcomes in patients with CHB. Methods: A retrospective study was conducted using the United States Inpatient Sample database on patients admitted with complete heart block. Outcomes were compared between the patients with and without concomitant malnutrition. Results: The study included 37,480 patients with complete heart block, of whom 603 (1.61%) had malnutrition. Compared to patients without malnutrition, patients with malnutrition had higher adjusted in-hospital mortality rates (aOR 2.61; 95% CI 1.46–3.48), longer length of stay (LOS) (mean increase 2.23 days; <i>p</i> < 0.01), and higher hospital charges (mean increase USD 76,907.32; <i>p</i> < 0.01). The malnourished group also had significantly higher rates of cardiogenic shock (aOR 2.80; 95% CI 1.56–5.03; <i>p</i> < 0.01) and acute respiratory failure (aOR 2.65; 95% CI 1.67–4.22; <i>p</i> < 0.01). Patients with malnutrition had significantly lower rates of permanent pacemaker (aOR 0.57; 95% CI 0.38–0.86; <i>p</i> < 0.01) and longer delay to permanent pacemaker intervention (mean increase 1.38 days; <i>p</i> = 0.014). The impact on outcomes was worse in patients with severe malnutrition compared to those with mild to moderate malnutrition. Conclusions: Malnutrition is associated with significantly worse outcomes in CHB admissions, including higher mortality, resource utilization, complications, and lower and delayed pacemaker intervention. Individualized and timely nutritional interventions might potentially play a key role in improving outcomes in these patients.https://www.mdpi.com/2673-4168/5/1/18complete heart blockmalnutritionpermanent pacemakernational inpatient databasemortalitylength of stay |
| spellingShingle | Nahush Bansal Sonaal Singla Jasneet Kaur Nikita Sharma Feehaan Sultan Shuhao Qiu Association of Malnutrition in Patients Admitted with Complete Heart Block: A Nationwide Analysis Obesities complete heart block malnutrition permanent pacemaker national inpatient database mortality length of stay |
| title | Association of Malnutrition in Patients Admitted with Complete Heart Block: A Nationwide Analysis |
| title_full | Association of Malnutrition in Patients Admitted with Complete Heart Block: A Nationwide Analysis |
| title_fullStr | Association of Malnutrition in Patients Admitted with Complete Heart Block: A Nationwide Analysis |
| title_full_unstemmed | Association of Malnutrition in Patients Admitted with Complete Heart Block: A Nationwide Analysis |
| title_short | Association of Malnutrition in Patients Admitted with Complete Heart Block: A Nationwide Analysis |
| title_sort | association of malnutrition in patients admitted with complete heart block a nationwide analysis |
| topic | complete heart block malnutrition permanent pacemaker national inpatient database mortality length of stay |
| url | https://www.mdpi.com/2673-4168/5/1/18 |
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