A Case of Hypocalcemia with Severe Vitamin D Deficiency following Treatment for Graves’ Disease with Methimazole
We herein report the case of a 41-year-old Japanese female office worker who developed symptomatic hypocalcemia with severe vitamin D deficiency following treatment for Graves’ disease with methimazole. The patient’s hypocalcemia was mainly caused by vitamin D deficiency due to unbalanced diets and...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2013/512671 |
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| author | Kazuyuki Miyashita Tetsuyuki Yasuda Hideaki Kaneto Akio Kuroda Tetsuhiro Kitamura Michio Otsuki Yasuyuki Okamoto Noboru Hamada Munehide Matsuhisa Iichiro Shimomura |
| author_facet | Kazuyuki Miyashita Tetsuyuki Yasuda Hideaki Kaneto Akio Kuroda Tetsuhiro Kitamura Michio Otsuki Yasuyuki Okamoto Noboru Hamada Munehide Matsuhisa Iichiro Shimomura |
| author_sort | Kazuyuki Miyashita |
| collection | DOAJ |
| description | We herein report the case of a 41-year-old Japanese female office worker who developed symptomatic hypocalcemia with severe vitamin D deficiency following treatment for Graves’ disease with methimazole. The patient’s hypocalcemia was mainly caused by vitamin D deficiency due to unbalanced diets and inadequate exposure to sunlight in addition to the resolution of hyperthyroidism. Vitamin D deficiency is increasing worldwide, and it has been more recently shown to relate to the pathogenesis of Graves’ disease. However, vitamin D deficiency as a cause of hypocalcemia has received little attention. Taken together, this case suggests that we should take more care in calcium kinetics and vitamin D status during treatment for Graves’ disease with antithyroid drugs. |
| format | Article |
| id | doaj-art-8b30ab8b4ad54557ae9977a17782718e |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-8b30ab8b4ad54557ae9977a17782718e2025-02-03T06:44:46ZengWileyCase Reports in Endocrinology2090-65012090-651X2013-01-01201310.1155/2013/512671512671A Case of Hypocalcemia with Severe Vitamin D Deficiency following Treatment for Graves’ Disease with MethimazoleKazuyuki Miyashita0Tetsuyuki Yasuda1Hideaki Kaneto2Akio Kuroda3Tetsuhiro Kitamura4Michio Otsuki5Yasuyuki Okamoto6Noboru Hamada7Munehide Matsuhisa8Iichiro Shimomura9Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanDepartment of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanDepartment of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanDiabetes Therapeutics and Research Center, The University of Tokushima, Tokushima 770-8503, JapanDepartment of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanDepartment of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanSumire Clinic, Osaka 535-0031, JapanSumire Hospital, Osaka 536-0001, JapanDiabetes Therapeutics and Research Center, The University of Tokushima, Tokushima 770-8503, JapanDepartment of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanWe herein report the case of a 41-year-old Japanese female office worker who developed symptomatic hypocalcemia with severe vitamin D deficiency following treatment for Graves’ disease with methimazole. The patient’s hypocalcemia was mainly caused by vitamin D deficiency due to unbalanced diets and inadequate exposure to sunlight in addition to the resolution of hyperthyroidism. Vitamin D deficiency is increasing worldwide, and it has been more recently shown to relate to the pathogenesis of Graves’ disease. However, vitamin D deficiency as a cause of hypocalcemia has received little attention. Taken together, this case suggests that we should take more care in calcium kinetics and vitamin D status during treatment for Graves’ disease with antithyroid drugs.http://dx.doi.org/10.1155/2013/512671 |
| spellingShingle | Kazuyuki Miyashita Tetsuyuki Yasuda Hideaki Kaneto Akio Kuroda Tetsuhiro Kitamura Michio Otsuki Yasuyuki Okamoto Noboru Hamada Munehide Matsuhisa Iichiro Shimomura A Case of Hypocalcemia with Severe Vitamin D Deficiency following Treatment for Graves’ Disease with Methimazole Case Reports in Endocrinology |
| title | A Case of Hypocalcemia with Severe Vitamin D Deficiency following Treatment for Graves’ Disease with Methimazole |
| title_full | A Case of Hypocalcemia with Severe Vitamin D Deficiency following Treatment for Graves’ Disease with Methimazole |
| title_fullStr | A Case of Hypocalcemia with Severe Vitamin D Deficiency following Treatment for Graves’ Disease with Methimazole |
| title_full_unstemmed | A Case of Hypocalcemia with Severe Vitamin D Deficiency following Treatment for Graves’ Disease with Methimazole |
| title_short | A Case of Hypocalcemia with Severe Vitamin D Deficiency following Treatment for Graves’ Disease with Methimazole |
| title_sort | case of hypocalcemia with severe vitamin d deficiency following treatment for graves disease with methimazole |
| url | http://dx.doi.org/10.1155/2013/512671 |
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