Diet-Induced Obesity Alters Granulosa Cell Transcriptome and Ovarian Immune Environment in Mice

Diet-Induced Obesity Alters Granulosa Cell Transcriptome and Ovarian Immune Environment in Mice

Obesity affects female reproductive performance by impairing the ovarian and uterine environments. Using a diet-induced obesity mouse model, we examined whether a high-fat diet (HFD) regimen affects the gene expression profile in ovarian granulosa cells (GCs) and whether short-term HFD has similar e...

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Bibliographic Details
Main Authors: Minseo Lee, Sujin Son, Surim Oh, Eunbin Shin, Hyejin Shin, Ohrim Kwon, Sohyun Hwang, Haengseok Song, Hyunjung Jade Lim
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Life
Subjects:
granulosa cell
obesity
mouse
ovary
<i>Egr1</i>
Online Access:https://www.mdpi.com/2075-1729/15/3/330
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