The Impact of Maternal Spinal Anesthesia on Newborn Out-Comes: A Clinical Perspective
Background/Objectives: Spinal anesthesia, frequently used in cesarean deliveries, can have a significant impact on newborns. This study aims to evaluate the effects of spinal anesthesia with morphine or fentanyl as adjuvants on neonatal outcomes. Methods: A retrospective study was conducted over a s...
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MDPI AG
2025-03-01
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| Series: | Children |
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| author | Ramona Celia Moisa Nicoleta Negrut Iulia Codruta Macovei Cristina Aur Mihai Octavian Botea Paula Bianca Maghiar Cezar Cristian Mihai Moisa Harrie Toms John Paula Marian |
| author_facet | Ramona Celia Moisa Nicoleta Negrut Iulia Codruta Macovei Cristina Aur Mihai Octavian Botea Paula Bianca Maghiar Cezar Cristian Mihai Moisa Harrie Toms John Paula Marian |
| author_sort | Ramona Celia Moisa |
| collection | DOAJ |
| description | Background/Objectives: Spinal anesthesia, frequently used in cesarean deliveries, can have a significant impact on newborns. This study aims to evaluate the effects of spinal anesthesia with morphine or fentanyl as adjuvants on neonatal outcomes. Methods: A retrospective study was conducted over a specific period on 170 newborns delivered via cesarean section at the Pelican Clinic, Medicover Hospital, Romania. The neonatal parameters assessed included Apgar scores at 1 and 5 min, oxygen saturation, respiratory rate, and heart rate in two groups of newborns whose mothers underwent spinal anesthesia with bupivacaine combined with either morphine or fentanyl (group M_n and group F_n). Statistical analysis was performed using IBM SPSS Statistics (version 29.0.2.0 (20)). Results: Newborns in the M_n group had significantly higher Apgar scores at 1 min compared to those in the F_n group (9.63 ± 0.57 vs 9.40 ± 0.65, <i>p</i> = 0.010); however, at 5 min, the scores were comparable between groups. Regarding oxygen saturation, male neonates born to mothers who received morphine had significantly higher values than those in the fentanyl group (96.08 ± 4.14% vs. 94.50 ± 4.36%, <i>p</i> = 0.026), whereas no significant differences were observed in female neonates. Conclusions: The use of morphine in maternal spinal anesthesia may improve immediate neonatal adaptation, particularly in male newborns. |
| format | Article |
| id | doaj-art-8b07d9160741443c823b4d02cbbd2261 |
| institution | DOAJ |
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| language | English |
| publishDate | 2025-03-01 |
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| series | Children |
| spelling | doaj-art-8b07d9160741443c823b4d02cbbd22612025-08-20T03:13:46ZengMDPI AGChildren2227-90672025-03-0112445010.3390/children12040450The Impact of Maternal Spinal Anesthesia on Newborn Out-Comes: A Clinical PerspectiveRamona Celia Moisa0Nicoleta Negrut1Iulia Codruta Macovei2Cristina Aur3Mihai Octavian Botea4Paula Bianca Maghiar5Cezar Cristian Mihai Moisa6Harrie Toms John7Paula Marian8Clinic of Anaesthesia and Intensive Care, Pelican Clinic, Medicover Hospital, 4104869 Oradea, RomaniaDoctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, RomaniaDepartment of Surgery, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, RomaniaDepartment of Surgery, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, RomaniaClinic of Anaesthesia and Intensive Care, Pelican Clinic, Medicover Hospital, 4104869 Oradea, RomaniaDoctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, RomaniaFaculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, RomaniaDepartment of Intensive Care, Epsom and St. Helier University Hospitals NHS Trust, Wrythe Lane, Sutton, Carshalton SM5 1AA, UKDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, RomaniaBackground/Objectives: Spinal anesthesia, frequently used in cesarean deliveries, can have a significant impact on newborns. This study aims to evaluate the effects of spinal anesthesia with morphine or fentanyl as adjuvants on neonatal outcomes. Methods: A retrospective study was conducted over a specific period on 170 newborns delivered via cesarean section at the Pelican Clinic, Medicover Hospital, Romania. The neonatal parameters assessed included Apgar scores at 1 and 5 min, oxygen saturation, respiratory rate, and heart rate in two groups of newborns whose mothers underwent spinal anesthesia with bupivacaine combined with either morphine or fentanyl (group M_n and group F_n). Statistical analysis was performed using IBM SPSS Statistics (version 29.0.2.0 (20)). Results: Newborns in the M_n group had significantly higher Apgar scores at 1 min compared to those in the F_n group (9.63 ± 0.57 vs 9.40 ± 0.65, <i>p</i> = 0.010); however, at 5 min, the scores were comparable between groups. Regarding oxygen saturation, male neonates born to mothers who received morphine had significantly higher values than those in the fentanyl group (96.08 ± 4.14% vs. 94.50 ± 4.36%, <i>p</i> = 0.026), whereas no significant differences were observed in female neonates. Conclusions: The use of morphine in maternal spinal anesthesia may improve immediate neonatal adaptation, particularly in male newborns.https://www.mdpi.com/2227-9067/12/4/450spinal anesthesiamorphinefentanylApgar |
| spellingShingle | Ramona Celia Moisa Nicoleta Negrut Iulia Codruta Macovei Cristina Aur Mihai Octavian Botea Paula Bianca Maghiar Cezar Cristian Mihai Moisa Harrie Toms John Paula Marian The Impact of Maternal Spinal Anesthesia on Newborn Out-Comes: A Clinical Perspective Children spinal anesthesia morphine fentanyl Apgar |
| title | The Impact of Maternal Spinal Anesthesia on Newborn Out-Comes: A Clinical Perspective |
| title_full | The Impact of Maternal Spinal Anesthesia on Newborn Out-Comes: A Clinical Perspective |
| title_fullStr | The Impact of Maternal Spinal Anesthesia on Newborn Out-Comes: A Clinical Perspective |
| title_full_unstemmed | The Impact of Maternal Spinal Anesthesia on Newborn Out-Comes: A Clinical Perspective |
| title_short | The Impact of Maternal Spinal Anesthesia on Newborn Out-Comes: A Clinical Perspective |
| title_sort | impact of maternal spinal anesthesia on newborn out comes a clinical perspective |
| topic | spinal anesthesia morphine fentanyl Apgar |
| url | https://www.mdpi.com/2227-9067/12/4/450 |
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