Multiscale Fuzzy Entropy Analysis of Balance: Evidences of Scale-Dependent Dynamics on Diabetic Patients With and Without Neuropathy
Postural control is usually assessed by examining the fluctuations of the center of pressure (COP). Balance maintenance is based on sensory feedback and neural interactions, deployed over multiple temporal scales and producing less complex outputs with aging and disease. This paper aims to investiga...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IEEE
2023-01-01
|
| Series: | IEEE Transactions on Neural Systems and Rehabilitation Engineering |
| Subjects: | |
| Online Access: | https://ieeexplore.ieee.org/document/10050866/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850271655425736704 |
|---|---|
| author | Alessandro Mengarelli Andrea Tigrini Federica Verdini Rosa Anna Rabini Sandro Fioretti |
| author_facet | Alessandro Mengarelli Andrea Tigrini Federica Verdini Rosa Anna Rabini Sandro Fioretti |
| author_sort | Alessandro Mengarelli |
| collection | DOAJ |
| description | Postural control is usually assessed by examining the fluctuations of the center of pressure (COP). Balance maintenance is based on sensory feedback and neural interactions, deployed over multiple temporal scales and producing less complex outputs with aging and disease. This paper aims to investigate postural dynamics and complexity on diabetic patients, since diabetic neuropathy (DN) affects the somatosensory system and impairs postural steadiness. A multiscale fuzzy entropy (MSFEn) analysis, over a wide range of temporal scales, was performed on COP timeseries during unperturbed stance in a group of diabetic individuals without neuropathy and two groups of DN patients, with and without symptoms. A parameterization of the MSFEn curve is also proposed. A significant loss of complexity was recognized for the medial-lateral direction in DN groups with respect to non-neuropathic population. For the anterior-posterior direction, symptomatic DN group showed a lowered sway complexity for longer time scales with respect to non neuropathic and asymptomatic patients. The MSFEn approach and the related parameters highlighted that the loss of complexity might be attributed to different factors depending on sway direction, i.e. related to the presence of neuropathy along the medial-lateral axis and to a symptomatic state on the anterior-posterior direction. Results of this study support the use of the MSFEn for gaining insights into balance control mechanisms for diabetic patients, in particular when comparing non neuropathic with neuropathic asymptomatic patients, whose identification by posturographic analysis would be of great value. |
| format | Article |
| id | doaj-art-8b03162bdc3b466ea208d9c8c54e6106 |
| institution | OA Journals |
| issn | 1534-4320 1558-0210 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | IEEE |
| record_format | Article |
| series | IEEE Transactions on Neural Systems and Rehabilitation Engineering |
| spelling | doaj-art-8b03162bdc3b466ea208d9c8c54e61062025-08-20T01:52:10ZengIEEEIEEE Transactions on Neural Systems and Rehabilitation Engineering1534-43201558-02102023-01-01311462147110.1109/TNSRE.2023.324832210050866Multiscale Fuzzy Entropy Analysis of Balance: Evidences of Scale-Dependent Dynamics on Diabetic Patients With and Without NeuropathyAlessandro Mengarelli0https://orcid.org/0000-0002-6087-6763Andrea Tigrini1https://orcid.org/0000-0002-1600-2137Federica Verdini2https://orcid.org/0000-0003-4252-3224Rosa Anna Rabini3https://orcid.org/0009-0000-2714-6753Sandro Fioretti4https://orcid.org/0000-0002-7783-3065Department of Information Engineering, Università Politecnica delle Marche, Ancona, ItalyDepartment of Information Engineering, Università Politecnica delle Marche, Ancona, ItalyDepartment of Information Engineering, Università Politecnica delle Marche, Ancona, ItalyDepartment of Diabetology, Mazzoni Hospital, Ascoli Piceno, ItalyDepartment of Information Engineering, Università Politecnica delle Marche, Ancona, ItalyPostural control is usually assessed by examining the fluctuations of the center of pressure (COP). Balance maintenance is based on sensory feedback and neural interactions, deployed over multiple temporal scales and producing less complex outputs with aging and disease. This paper aims to investigate postural dynamics and complexity on diabetic patients, since diabetic neuropathy (DN) affects the somatosensory system and impairs postural steadiness. A multiscale fuzzy entropy (MSFEn) analysis, over a wide range of temporal scales, was performed on COP timeseries during unperturbed stance in a group of diabetic individuals without neuropathy and two groups of DN patients, with and without symptoms. A parameterization of the MSFEn curve is also proposed. A significant loss of complexity was recognized for the medial-lateral direction in DN groups with respect to non-neuropathic population. For the anterior-posterior direction, symptomatic DN group showed a lowered sway complexity for longer time scales with respect to non neuropathic and asymptomatic patients. The MSFEn approach and the related parameters highlighted that the loss of complexity might be attributed to different factors depending on sway direction, i.e. related to the presence of neuropathy along the medial-lateral axis and to a symptomatic state on the anterior-posterior direction. Results of this study support the use of the MSFEn for gaining insights into balance control mechanisms for diabetic patients, in particular when comparing non neuropathic with neuropathic asymptomatic patients, whose identification by posturographic analysis would be of great value.https://ieeexplore.ieee.org/document/10050866/Multiscale entropyfuzzy entropydiabetescenter of pressureneuropathy |
| spellingShingle | Alessandro Mengarelli Andrea Tigrini Federica Verdini Rosa Anna Rabini Sandro Fioretti Multiscale Fuzzy Entropy Analysis of Balance: Evidences of Scale-Dependent Dynamics on Diabetic Patients With and Without Neuropathy IEEE Transactions on Neural Systems and Rehabilitation Engineering Multiscale entropy fuzzy entropy diabetes center of pressure neuropathy |
| title | Multiscale Fuzzy Entropy Analysis of Balance: Evidences of Scale-Dependent Dynamics on Diabetic Patients With and Without Neuropathy |
| title_full | Multiscale Fuzzy Entropy Analysis of Balance: Evidences of Scale-Dependent Dynamics on Diabetic Patients With and Without Neuropathy |
| title_fullStr | Multiscale Fuzzy Entropy Analysis of Balance: Evidences of Scale-Dependent Dynamics on Diabetic Patients With and Without Neuropathy |
| title_full_unstemmed | Multiscale Fuzzy Entropy Analysis of Balance: Evidences of Scale-Dependent Dynamics on Diabetic Patients With and Without Neuropathy |
| title_short | Multiscale Fuzzy Entropy Analysis of Balance: Evidences of Scale-Dependent Dynamics on Diabetic Patients With and Without Neuropathy |
| title_sort | multiscale fuzzy entropy analysis of balance evidences of scale dependent dynamics on diabetic patients with and without neuropathy |
| topic | Multiscale entropy fuzzy entropy diabetes center of pressure neuropathy |
| url | https://ieeexplore.ieee.org/document/10050866/ |
| work_keys_str_mv | AT alessandromengarelli multiscalefuzzyentropyanalysisofbalanceevidencesofscaledependentdynamicsondiabeticpatientswithandwithoutneuropathy AT andreatigrini multiscalefuzzyentropyanalysisofbalanceevidencesofscaledependentdynamicsondiabeticpatientswithandwithoutneuropathy AT federicaverdini multiscalefuzzyentropyanalysisofbalanceevidencesofscaledependentdynamicsondiabeticpatientswithandwithoutneuropathy AT rosaannarabini multiscalefuzzyentropyanalysisofbalanceevidencesofscaledependentdynamicsondiabeticpatientswithandwithoutneuropathy AT sandrofioretti multiscalefuzzyentropyanalysisofbalanceevidencesofscaledependentdynamicsondiabeticpatientswithandwithoutneuropathy |