Identification of prognostic biomarkers related to epithelial-mesenchymal transition and anoikis in hepatocellular carcinoma using transcriptomics and single-cell sequencing

Identification of prognostic biomarkers related to epithelial-mesenchymal transition and anoikis in hepatocellular carcinoma using transcriptomics and single-cell sequencing

BackgroundEpithelial-mesenchymal transition (EMT) and anoikis are critically associated with hepatocellular carcinoma (HCC). However, the precise mechanisms underlying their roles in HCC remain unclear. This study aims to explore the involvement of EMT-related genes (EMTRGs) and anoikis-related gene...

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Bibliographic Details
Main Authors: Maobing Wang, Lu Cheng, Kuo Qi, Haiping Wang, Xun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hepatocellular carcinoma
epithelial mesenchymal transition
anoikis
single-cell RNA sequencing
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1600546/full
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