The association between anthocyanin intake and myopia in adolescents: a cross-sectional study of NHANES
AimThe study aimed to explore the relationship of anthocyanin and its subtypes with myopia in adolescents aged 12–17 years.MethodsAdolescents data for this cross-sectional study were extracted from the National Health and Nutrition Examination Survey (NHANES) 2007–2008. Anthocyanin and subtypes were...
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Frontiers Media S.A.
2024-11-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2024.1503926/full |
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| author | Ying Chen Ying Chen Ying Chen Qinglin Xu Qinglin Xu Lu Lv Lu Lv Yun Liu Yun Liu Zhidan Zhang Zhidan Zhang Zhikuan Yang |
| author_facet | Ying Chen Ying Chen Ying Chen Qinglin Xu Qinglin Xu Lu Lv Lu Lv Yun Liu Yun Liu Zhidan Zhang Zhidan Zhang Zhikuan Yang |
| author_sort | Ying Chen |
| collection | DOAJ |
| description | AimThe study aimed to explore the relationship of anthocyanin and its subtypes with myopia in adolescents aged 12–17 years.MethodsAdolescents data for this cross-sectional study were extracted from the National Health and Nutrition Examination Survey (NHANES) 2007–2008. Anthocyanin and subtypes were obtained using the Nutrient Database for Dietary Studies codes. Myopia was defined as a spherical equivalent of −1.0 diopters or less. The relationships between anthocyanin and subtypes intake and myopia were determined utilizing weighted univariate and multivariate logistic regression models. The relationships were also explored in gender, leisure time, physical activity, sedentary activity, BMI, and serum cotinine subgroups.ResultsA total of 839 adolescents were included for further analysis, among them 245 have myopia. Malvidin (34.98%) was the subtype with the largest anthocyanin intake, followed by cyanidin (22.94%). Compared to adolescents without anthocyanin intake, total anthocyanin intake was related to a lower incidence of myopia (OR = 0.69, 95%CI: 0.51–0.92). Higher intake of cyanidin (OR = 0.69, 95%CI: 0.52–0.92), petunidin (OR = 0.64, 95%CI: 0.42–0.97), and delphinidin (OR = 0.71, 95%CI: 0.51–0.99) were associated with lower odds of myopia in adolescents. Higher total anthocyanin intake was related to lower odds of myopia in those females, leisure time physical activity ≥60 min/day, sedentary time <8 h/day, overweight or obese, and serum cotinine ≥0.05 ng/ml.ConclusionHigher total anthocyanin intake, particularly cyanidin, petunidin, and delphinidin, was related to a lower incidence of myopia in adolescents. Increasing dietary anthocyanin intake may be an effective prevention strategy for ocular health. |
| format | Article |
| id | doaj-art-8ae47bcf3cd346eebb6859b0580efcd1 |
| institution | Kabale University |
| issn | 2296-2360 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj-art-8ae47bcf3cd346eebb6859b0580efcd12024-11-15T04:51:59ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602024-11-011210.3389/fped.2024.15039261503926The association between anthocyanin intake and myopia in adolescents: a cross-sectional study of NHANESYing Chen0Ying Chen1Ying Chen2Qinglin Xu3Qinglin Xu4Lu Lv5Lu Lv6Yun Liu7Yun Liu8Zhidan Zhang9Zhidan Zhang10Zhikuan Yang11Department of Optometry and Pediatric Ophthalmology, Aier Eye Hospital, Jinan University, Guangzhou, Guangdong, ChinaDepartment of Pediatric Ophthalmology, Aier Eye Hospital of Wuhan University (Wuhan Aier Eye Hospital), Wuhan, Hubei, ChinaDepartment of Optometry and Pediatric Ophthalmology, Hankou Aier Eye Hospital, Wuhan, Hubei, ChinaDepartment of Optometry and Pediatric Ophthalmology, Aier Eye Hospital, Jinan University, Guangzhou, Guangdong, ChinaDepartment of Optometry and Pediatric Ophthalmology, Changsha Aier Eye Hospital, Changsha, Hunan, ChinaDepartment of Pediatric Ophthalmology, Aier Eye Hospital of Wuhan University (Wuhan Aier Eye Hospital), Wuhan, Hubei, ChinaDepartment of Optometry and Pediatric Ophthalmology, Hankou Aier Eye Hospital, Wuhan, Hubei, ChinaDepartment of Pediatric Ophthalmology, Aier Eye Hospital of Wuhan University (Wuhan Aier Eye Hospital), Wuhan, Hubei, ChinaDepartment of Optometry and Pediatric Ophthalmology, Hankou Aier Eye Hospital, Wuhan, Hubei, ChinaDepartment of Pediatric Ophthalmology, Aier Eye Hospital of Wuhan University (Wuhan Aier Eye Hospital), Wuhan, Hubei, ChinaDepartment of Optometry and Pediatric Ophthalmology, Hankou Aier Eye Hospital, Wuhan, Hubei, ChinaDepartment of Optometry and Pediatric Ophthalmology, Aier Eye Hospital, Jinan University, Guangzhou, Guangdong, ChinaAimThe study aimed to explore the relationship of anthocyanin and its subtypes with myopia in adolescents aged 12–17 years.MethodsAdolescents data for this cross-sectional study were extracted from the National Health and Nutrition Examination Survey (NHANES) 2007–2008. Anthocyanin and subtypes were obtained using the Nutrient Database for Dietary Studies codes. Myopia was defined as a spherical equivalent of −1.0 diopters or less. The relationships between anthocyanin and subtypes intake and myopia were determined utilizing weighted univariate and multivariate logistic regression models. The relationships were also explored in gender, leisure time, physical activity, sedentary activity, BMI, and serum cotinine subgroups.ResultsA total of 839 adolescents were included for further analysis, among them 245 have myopia. Malvidin (34.98%) was the subtype with the largest anthocyanin intake, followed by cyanidin (22.94%). Compared to adolescents without anthocyanin intake, total anthocyanin intake was related to a lower incidence of myopia (OR = 0.69, 95%CI: 0.51–0.92). Higher intake of cyanidin (OR = 0.69, 95%CI: 0.52–0.92), petunidin (OR = 0.64, 95%CI: 0.42–0.97), and delphinidin (OR = 0.71, 95%CI: 0.51–0.99) were associated with lower odds of myopia in adolescents. Higher total anthocyanin intake was related to lower odds of myopia in those females, leisure time physical activity ≥60 min/day, sedentary time <8 h/day, overweight or obese, and serum cotinine ≥0.05 ng/ml.ConclusionHigher total anthocyanin intake, particularly cyanidin, petunidin, and delphinidin, was related to a lower incidence of myopia in adolescents. Increasing dietary anthocyanin intake may be an effective prevention strategy for ocular health.https://www.frontiersin.org/articles/10.3389/fped.2024.1503926/fulladolescentmyopiaadolescentscyanidinpetunidindelphinidin |
| spellingShingle | Ying Chen Ying Chen Ying Chen Qinglin Xu Qinglin Xu Lu Lv Lu Lv Yun Liu Yun Liu Zhidan Zhang Zhidan Zhang Zhikuan Yang The association between anthocyanin intake and myopia in adolescents: a cross-sectional study of NHANES Frontiers in Pediatrics adolescent myopia adolescents cyanidin petunidin delphinidin |
| title | The association between anthocyanin intake and myopia in adolescents: a cross-sectional study of NHANES |
| title_full | The association between anthocyanin intake and myopia in adolescents: a cross-sectional study of NHANES |
| title_fullStr | The association between anthocyanin intake and myopia in adolescents: a cross-sectional study of NHANES |
| title_full_unstemmed | The association between anthocyanin intake and myopia in adolescents: a cross-sectional study of NHANES |
| title_short | The association between anthocyanin intake and myopia in adolescents: a cross-sectional study of NHANES |
| title_sort | association between anthocyanin intake and myopia in adolescents a cross sectional study of nhanes |
| topic | adolescent myopia adolescents cyanidin petunidin delphinidin |
| url | https://www.frontiersin.org/articles/10.3389/fped.2024.1503926/full |
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