Mouse Models of Down Syndrome as a Tool to Unravel the Causes of Mental Disabilities
Down syndrome (DS) is the most common genetic cause of mental disability. Based on the homology of Hsa21 and the murine chromosomes Mmu16, Mmu17 and Mmu10, several mouse models of DS have been developed. The most commonly used model, the Ts65Dn mouse, has been widely used to investigate the neural m...
Saved in:
| Main Authors: | Noemí Rueda, Jesús Flórez, Carmen Martínez-Cué |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2012/584071 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Quantitative PCR genotyping assay for the Ts65Dn mouse model of Down syndrome
by: Dong P. Liu, et al.
Published: (2003-12-01) -
Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome.
by: Jamie R K Marland, et al.
Published: (2016-01-01) -
Interferon signaling modulates Down syndrome-associated Alzheimer’s disease pathology in a mouse model
by: Paula Araya, et al.
Published: (2025-08-01) -
Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome.
by: Nick M Powell, et al.
Published: (2016-01-01) -
An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.
by: Pavel V Belichenko, et al.
Published: (2016-01-01)