By activating endothelium histone H4 mediates oleic acid-induced acute respiratory distress syndrome
Abstract Objective This study investigated pathogenic role and mechanism of extracellular histone H4 during oleic acid (OA)-induced acute respiratory distress syndrome (ARDS). Methods: ARDS was induced by intravenous injection of OA in mice, and evaluated by blood gas, pathological analysis, lung ed...
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| Main Authors: | Yanlin Zhang, Jingjin Tan, Yiran Zhao, Li Guan, Shuqiang Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-01-01
|
| Series: | BMC Pulmonary Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12890-024-03334-w |
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