Personal care products as a potential source of aquatic pollution: Effect of polyvinyl alcohol on physiological and antioxidant responses in Mytilus galloprovincialis

A high percentage of the broad spectrum of contaminants in aquatic environments is represented by personal care products (PCPs). Polyvinyl alcohol (PVA) is contained in the formulation of many of these products. The extensive use of PVA caused the annual release of over 65.000 tons into the environm...

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Main Authors: Cristiana Roberta Multisanti, Giorgia Zicarelli, Alessia Caferro, Mariacristina Filice, Jana Blahova, Irene Vazzana, Giuseppe Piccione, Sandra Imbrogno, Caterina Faggio, Federica Impellitteri
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325006724
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author Cristiana Roberta Multisanti
Giorgia Zicarelli
Alessia Caferro
Mariacristina Filice
Jana Blahova
Irene Vazzana
Giuseppe Piccione
Sandra Imbrogno
Caterina Faggio
Federica Impellitteri
author_facet Cristiana Roberta Multisanti
Giorgia Zicarelli
Alessia Caferro
Mariacristina Filice
Jana Blahova
Irene Vazzana
Giuseppe Piccione
Sandra Imbrogno
Caterina Faggio
Federica Impellitteri
author_sort Cristiana Roberta Multisanti
collection DOAJ
description A high percentage of the broad spectrum of contaminants in aquatic environments is represented by personal care products (PCPs). Polyvinyl alcohol (PVA) is contained in the formulation of many of these products. The extensive use of PVA caused the annual release of over 65.000 tons into the environment, constituting 1.2 % of particles in the Mediterranean Sea. For these reasons, the study aimed to investigate, for the first time in bivalve species, the possible cytotoxicity implications on non-target species, involved in the human food chain, caused by exposure to two different concentrations of PVA (PVA1: 0.1 mg L−1 and PVA2: 10 mg L−1). Following a fortnight of exposure, cell viability, regulation of cell volume decrease, oxidative stress, and biochemical parameters were evaluated. Moreover, the capability of the animal to produce byssal plaques was observed, representing a novelty for assessing the health status of mussels. The results showed a modification in the regulatory capacity of cell volume, particularly in those exposed to PVA2. An alteration in the superoxide dismutase activity (in PVA2) and in the levels of oxidatively modified proteins (PVA1 and PVA2) was detected in gills. A modification in the byssal plaque production following PVA exposure was also observed. These findings enrich the knowledge about the interaction between PVA and organisms, underscoring further research's need to elucidate the environmental implications.
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spelling doaj-art-8abf7890fbd44524b6e043b9f82a0ea42025-08-20T02:26:07ZengElsevierEcotoxicology and Environmental Safety0147-65132025-06-0129811833610.1016/j.ecoenv.2025.118336Personal care products as a potential source of aquatic pollution: Effect of polyvinyl alcohol on physiological and antioxidant responses in Mytilus galloprovincialisCristiana Roberta Multisanti0Giorgia Zicarelli1Alessia Caferro2Mariacristina Filice3Jana Blahova4Irene Vazzana5Giuseppe Piccione6Sandra Imbrogno7Caterina Faggio8Federica Impellitteri9Department of Veterinary Sciences, University of Messina, Viale Giovanni Palatucci snc, Messina 98168, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d’Alcontres, 31, Messina 98166, ItalyDepartment of Biology, Ecology and Earth Science, University of Calabria, Rende 87036, ItalyDepartment of Biology, Ecology and Earth Science, University of Calabria, Rende 87036, ItalyDepartment of Animal Protection and Welfare & Veterinary Public Health, Faculty of Veterinary Hygiene and Ecology, University of Veterinary Sciences Brno, Palackeho tr. 1946/1, Brno 612 42, Czech RepublicZooprophylactic Institute of Sicily, Via Gino Marinuzzi, Palermo 90129, ItalyDepartment of Veterinary Sciences, University of Messina, Viale Giovanni Palatucci snc, Messina 98168, ItalyDepartment of Biology, Ecology and Earth Science, University of Calabria, Rende 87036, Italy; Corresponding author.Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d’Alcontres, 31, Messina 98166, Italy; Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy; Corresponding author at: Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d’Alcontres, 31, Messina 98166, ItalyDepartment of Veterinary Sciences, University of Messina, Viale Giovanni Palatucci snc, Messina 98168, ItalyA high percentage of the broad spectrum of contaminants in aquatic environments is represented by personal care products (PCPs). Polyvinyl alcohol (PVA) is contained in the formulation of many of these products. The extensive use of PVA caused the annual release of over 65.000 tons into the environment, constituting 1.2 % of particles in the Mediterranean Sea. For these reasons, the study aimed to investigate, for the first time in bivalve species, the possible cytotoxicity implications on non-target species, involved in the human food chain, caused by exposure to two different concentrations of PVA (PVA1: 0.1 mg L−1 and PVA2: 10 mg L−1). Following a fortnight of exposure, cell viability, regulation of cell volume decrease, oxidative stress, and biochemical parameters were evaluated. Moreover, the capability of the animal to produce byssal plaques was observed, representing a novelty for assessing the health status of mussels. The results showed a modification in the regulatory capacity of cell volume, particularly in those exposed to PVA2. An alteration in the superoxide dismutase activity (in PVA2) and in the levels of oxidatively modified proteins (PVA1 and PVA2) was detected in gills. A modification in the byssal plaque production following PVA exposure was also observed. These findings enrich the knowledge about the interaction between PVA and organisms, underscoring further research's need to elucidate the environmental implications.http://www.sciencedirect.com/science/article/pii/S0147651325006724Water-soluble polymerMusselsMarine environmentAquatic pollution
spellingShingle Cristiana Roberta Multisanti
Giorgia Zicarelli
Alessia Caferro
Mariacristina Filice
Jana Blahova
Irene Vazzana
Giuseppe Piccione
Sandra Imbrogno
Caterina Faggio
Federica Impellitteri
Personal care products as a potential source of aquatic pollution: Effect of polyvinyl alcohol on physiological and antioxidant responses in Mytilus galloprovincialis
Ecotoxicology and Environmental Safety
Water-soluble polymer
Mussels
Marine environment
Aquatic pollution
title Personal care products as a potential source of aquatic pollution: Effect of polyvinyl alcohol on physiological and antioxidant responses in Mytilus galloprovincialis
title_full Personal care products as a potential source of aquatic pollution: Effect of polyvinyl alcohol on physiological and antioxidant responses in Mytilus galloprovincialis
title_fullStr Personal care products as a potential source of aquatic pollution: Effect of polyvinyl alcohol on physiological and antioxidant responses in Mytilus galloprovincialis
title_full_unstemmed Personal care products as a potential source of aquatic pollution: Effect of polyvinyl alcohol on physiological and antioxidant responses in Mytilus galloprovincialis
title_short Personal care products as a potential source of aquatic pollution: Effect of polyvinyl alcohol on physiological and antioxidant responses in Mytilus galloprovincialis
title_sort personal care products as a potential source of aquatic pollution effect of polyvinyl alcohol on physiological and antioxidant responses in mytilus galloprovincialis
topic Water-soluble polymer
Mussels
Marine environment
Aquatic pollution
url http://www.sciencedirect.com/science/article/pii/S0147651325006724
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