Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities

Medical imaging is critical in modern healthcare for accurately detecting and diagnosing various medical conditions. Advanced computational techniques, particularly preprocessing methods and deep learning models, have demonstrated significant potential for improving medical image analysis. However,...

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Main Authors: Thien B. Nguyen-Tat, Tran Quang Hung, Pham Tien Nam, Vuong M. Ngo
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Alexandria Engineering Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S1110016825001176
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author Thien B. Nguyen-Tat
Tran Quang Hung
Pham Tien Nam
Vuong M. Ngo
author_facet Thien B. Nguyen-Tat
Tran Quang Hung
Pham Tien Nam
Vuong M. Ngo
author_sort Thien B. Nguyen-Tat
collection DOAJ
description Medical imaging is critical in modern healthcare for accurately detecting and diagnosing various medical conditions. Advanced computational techniques, particularly preprocessing methods and deep learning models, have demonstrated significant potential for improving medical image analysis. However, determining the optimal combination of these techniques across different types of medical images remains a challenge. Using empirical experiments, this evaluation research investigates the effectiveness of five popular pairs of preprocessing techniques combined with five widely used deep learning models. Preprocessing methods evaluated include CLAHE + Butterworth, DWT + Threshold, CLAHE + median filter, Median-Mean Hybrid Filter, and Unsharp Masking + Bilateral Filter, concatenated with deep learning models: EfficiencyNet-B4, ResNet-50, DenseNet-169, VGG16 and MobileNetV2. The performance of these combinations was evaluated through experiments carried out on eight diverse and commonly used datasets encompassing various medical imaging modalities. These datasets include two X-ray collections: the COVID-19 Pneumonia Normal Chest PA Dataset and the Osteoporosis Knee X-ray Dataset; two CT scan datasets: the Chest CT-Scan Images Dataset and the Brain Stroke CT Image Dataset; two MRI datasets: the Breast Cancer Patients MRI and the Brain Tumor MRI Dataset; and two ultrasound datasets: the Ultrasound Breast Images for Breast Cancer and the MT Small Dataset. Our findings show that the Median-Mean Hybrid Filter and Unsharp Masking + Bilateral Filter are the most effective preprocessing methods, achieving an efficiency rate of 87.5%. Among the deep learning models, EfficiencyNet-B4 and MobileNetV2 are the highest performing models with an efficiency ratio of 75%, with MobileNetV2 providing up to 34% shorter runtime compared to other models. This study provides a thorough evaluation of the performance of different preprocessing methods and deep learning algorithms across commonly used medical imaging modalities. Presenting empirical results from our experiments offers practical insights into choosing the most suitable preprocessing techniques and deep learning models for various types of medical images. These findings are intended to support improvements in diagnostic accuracy and efficiency in medical imaging, offering a valuable reference for enhancing image-based diagnostic processes.
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spelling doaj-art-8abe463e6f7140cabd1fdc6d893acf022025-02-11T04:33:35ZengElsevierAlexandria Engineering Journal1110-01682025-04-01119558586Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalitiesThien B. Nguyen-Tat0Tran Quang Hung1Pham Tien Nam2Vuong M. Ngo3University of Information Technology, Ho Chi Minh City, Vietnam; Vietnam National University, Ho Chi Minh City, Vietnam; Corresponding author at: University of Information Technology, Ho Chi Minh City, Vietnam.University of Information Technology, Ho Chi Minh City, Vietnam; Vietnam National University, Ho Chi Minh City, VietnamUniversity of Information Technology, Ho Chi Minh City, Vietnam; Vietnam National University, Ho Chi Minh City, VietnamHo Chi Minh City Open University, Ho Chi Minh City, VietnamMedical imaging is critical in modern healthcare for accurately detecting and diagnosing various medical conditions. Advanced computational techniques, particularly preprocessing methods and deep learning models, have demonstrated significant potential for improving medical image analysis. However, determining the optimal combination of these techniques across different types of medical images remains a challenge. Using empirical experiments, this evaluation research investigates the effectiveness of five popular pairs of preprocessing techniques combined with five widely used deep learning models. Preprocessing methods evaluated include CLAHE + Butterworth, DWT + Threshold, CLAHE + median filter, Median-Mean Hybrid Filter, and Unsharp Masking + Bilateral Filter, concatenated with deep learning models: EfficiencyNet-B4, ResNet-50, DenseNet-169, VGG16 and MobileNetV2. The performance of these combinations was evaluated through experiments carried out on eight diverse and commonly used datasets encompassing various medical imaging modalities. These datasets include two X-ray collections: the COVID-19 Pneumonia Normal Chest PA Dataset and the Osteoporosis Knee X-ray Dataset; two CT scan datasets: the Chest CT-Scan Images Dataset and the Brain Stroke CT Image Dataset; two MRI datasets: the Breast Cancer Patients MRI and the Brain Tumor MRI Dataset; and two ultrasound datasets: the Ultrasound Breast Images for Breast Cancer and the MT Small Dataset. Our findings show that the Median-Mean Hybrid Filter and Unsharp Masking + Bilateral Filter are the most effective preprocessing methods, achieving an efficiency rate of 87.5%. Among the deep learning models, EfficiencyNet-B4 and MobileNetV2 are the highest performing models with an efficiency ratio of 75%, with MobileNetV2 providing up to 34% shorter runtime compared to other models. This study provides a thorough evaluation of the performance of different preprocessing methods and deep learning algorithms across commonly used medical imaging modalities. Presenting empirical results from our experiments offers practical insights into choosing the most suitable preprocessing techniques and deep learning models for various types of medical images. These findings are intended to support improvements in diagnostic accuracy and efficiency in medical imaging, offering a valuable reference for enhancing image-based diagnostic processes.http://www.sciencedirect.com/science/article/pii/S1110016825001176Medical image preprocessingDeep learning modelsPreprocessing and model combinationDiagnostic accuracyResource efficiency
spellingShingle Thien B. Nguyen-Tat
Tran Quang Hung
Pham Tien Nam
Vuong M. Ngo
Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities
Alexandria Engineering Journal
Medical image preprocessing
Deep learning models
Preprocessing and model combination
Diagnostic accuracy
Resource efficiency
title Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities
title_full Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities
title_fullStr Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities
title_full_unstemmed Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities
title_short Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities
title_sort evaluating pre processing and deep learning methods in medical imaging combined effectiveness across multiple modalities
topic Medical image preprocessing
Deep learning models
Preprocessing and model combination
Diagnostic accuracy
Resource efficiency
url http://www.sciencedirect.com/science/article/pii/S1110016825001176
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