A review on diagnosis and treatment approaches to calcium pyrophosphate deposition disease
Introduction and purpose of this work CPPD is an arthropathy related to calcium pyrophosphate crystals’ deposition in joints triggering an inflammatory response leading to local articular damage. CPPD mainly affects the large and weight-bearing joints.In this review paper, our aim is to outline...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2024-12-01
|
| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/56618 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846113515075534848 |
|---|---|
| author | Negar Hosseinnejad Aleksandra Cygnarowicz Aneta Klaudia Wojtas Krystyna Zabojska Urszula Korotko Aneta Mandziuk Kinga Witowska Mariola Turemka Mikolaj Biskupski Karolina Sacher |
| author_facet | Negar Hosseinnejad Aleksandra Cygnarowicz Aneta Klaudia Wojtas Krystyna Zabojska Urszula Korotko Aneta Mandziuk Kinga Witowska Mariola Turemka Mikolaj Biskupski Karolina Sacher |
| author_sort | Negar Hosseinnejad |
| collection | DOAJ |
| description |
Introduction and purpose of this work
CPPD is an arthropathy related to calcium pyrophosphate crystals’ deposition in joints triggering an inflammatory response leading to local articular damage. CPPD mainly affects the large and weight-bearing joints.In this review paper, our aim is to outline the current knowledge on epidemiology, origins, clinical manifest, diagnostical tools, new guidelines of the (ACR) and (EULAR) and current treatment options for CPPD.
Methods:
We performed a systematic electronic search on PubMed, Medline and Google Scholar databases. The search results were limited to publications from 2002 to 2024, as well as key studies and reference books from earlier years.
Brief description of the state of knowledge
CPP crystals in joints can lead to an inflammatory response and lead to joint damage. CPPD is the third most common reason of arthritis. Its origin is rather idiopathic, but there has been research showing the linkage of this disease to genetical background and some metabolic disorders.The treatment is chosen based on the phenotype of the disease.conventional pharmacological treatment includes NSAIDs, colchicine and corticosteroids. New opportunities to CPPD treatment have appeared thanks to biological medications which inhibit the inflammatory process.
Summary
Early diagnosis of CPPD, distinguishing it from other forms of arthritis and identifying the possible co-occurring diseases such as gout, rheumatoid arthritis and osteoporosis can help the clinicians to apply the proper treatment . Most patients are seniors with several comorbidities, this is why it is important to choose the right treatment, which prevents exacerbation of the inflammatory process and ensures high quality of life for the patients.
|
| format | Article |
| id | doaj-art-8ab6e1477509472c86de9342b81016b2 |
| institution | Kabale University |
| issn | 2391-8306 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj-art-8ab6e1477509472c86de9342b81016b22024-12-21T08:16:02ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062024-12-017610.12775/JEHS.2024.76.56618A review on diagnosis and treatment approaches to calcium pyrophosphate deposition diseaseNegar Hosseinnejad0https://orcid.org/0009-0002-3552-9513Aleksandra Cygnarowicz1https://orcid.org/0009-0002-2208-0104Aneta Klaudia Wojtas2https://orcid.org/0009-0002-6072-1232Krystyna Zabojska3https://orcid.org/0009-0002-6962-0497Urszula Korotko4https://orcid.org/0009-0004-9226-6451Aneta Mandziuk5https://orcid.org/0009-0001-2787-9479Kinga Witowska6https://orcid.org/0009-0003-2389-4887Mariola Turemka7https://orcid.org/0009-0001-8219-6515Mikolaj Biskupski8https://orcid.org/0009-0009-8103-4053Karolina Sacher9https://orcid.org/0009-0001-8875-5912The 5 Military Clinical Hospital with Polyclinic SPZOZ in Cracow, Wroclawska Street 1/3, 30-901 Cracow, Poland/ 5 Wojskowy Szpital Kliniczny z Polikliniką SPZOZ w Krakowie, ul. Wrocławska 1/3, 30-901 Kraków, PolskaBonifraters Medical Center sp. z. o. o. Branch in Krakow, Trynitarska 11 St., 31-061 Krakow, Poland "Municipal Hospital in Siemianowice Śląskie sp. z o.o., 1. Maja 9 St., 41-100 Siemianowice Śląskie, PolandHospital of Our Lady of Perpetual Help in Wolomin, Gdynska 1/3, 05-200 Wolomin, Poland / Szpital Matki Bożej Nieustającej Pomocy w Wołominie, Gdyńska 1/3, 05-250 WołominThe Provincial Specialist Hospital in Ciechanów, Powstańców Wielkopolskich 2 St., 06-400 Ciechanów, Poland/ Specjalistyczny Szpital Wojewódzki w CiechanowieIndependent Public Health Care Facility of the Ministry of Interior and Administration in Białystok/ Fabryczna Street 27 15-471 Białystok, PolandThe 5 Military Clinical Hospital with Polyclinic SPZOZ in Cracow, Wroclawska Street 1/3, 30-901 Cracow, Poland/ 5 Wojskowy Szpital Kliniczny z Polikliniką SPZOZ w Krakowie, ul. Wrocławska 1/3, 30-901 Kraków, PolskaVoivodeship Hospital in Bialystok/Marii Sklodowskiej-Curie 26, 15-278 Bialystok, Poland/ Wojewódzki Szpital Zespolony w Białymstoku, Marii Skłodowskiej-Curie 26, 15-278 BiałystokDepartment of Interventional Cardiology and Cardiac Arrhythmias, Teaching Hospital No. 2 of the Medical University of Lodz, Zeromskiego Street 113 90-549 Lodz, Poland/ Klinika Kardiologii Interwencyjnej i Zaburzeń Rytmu Serca, Uniwersytecki Szpital Kliniczny nr. 2 Uniwersytetu Medycznego w Łodzi, ul. Żeromskiego 113, 90-549 Łódź, PolskaŚląskie Centrum Chorób Serca Zabrze, Marii Skłodowskiej-Curie 9 / Silesian Center for Heart Diseases Zabrze, Marii Skłodowskiej-Curie 9 Introduction and purpose of this work CPPD is an arthropathy related to calcium pyrophosphate crystals’ deposition in joints triggering an inflammatory response leading to local articular damage. CPPD mainly affects the large and weight-bearing joints.In this review paper, our aim is to outline the current knowledge on epidemiology, origins, clinical manifest, diagnostical tools, new guidelines of the (ACR) and (EULAR) and current treatment options for CPPD. Methods: We performed a systematic electronic search on PubMed, Medline and Google Scholar databases. The search results were limited to publications from 2002 to 2024, as well as key studies and reference books from earlier years. Brief description of the state of knowledge CPP crystals in joints can lead to an inflammatory response and lead to joint damage. CPPD is the third most common reason of arthritis. Its origin is rather idiopathic, but there has been research showing the linkage of this disease to genetical background and some metabolic disorders.The treatment is chosen based on the phenotype of the disease.conventional pharmacological treatment includes NSAIDs, colchicine and corticosteroids. New opportunities to CPPD treatment have appeared thanks to biological medications which inhibit the inflammatory process. Summary Early diagnosis of CPPD, distinguishing it from other forms of arthritis and identifying the possible co-occurring diseases such as gout, rheumatoid arthritis and osteoporosis can help the clinicians to apply the proper treatment . Most patients are seniors with several comorbidities, this is why it is important to choose the right treatment, which prevents exacerbation of the inflammatory process and ensures high quality of life for the patients. https://apcz.umk.pl/JEHS/article/view/56618Calcium Pyrophosphate deposition diseasepharmacological treatmentbiological medicationsnon-pharmacological treatmentcriteria of CPPD diagnosis |
| spellingShingle | Negar Hosseinnejad Aleksandra Cygnarowicz Aneta Klaudia Wojtas Krystyna Zabojska Urszula Korotko Aneta Mandziuk Kinga Witowska Mariola Turemka Mikolaj Biskupski Karolina Sacher A review on diagnosis and treatment approaches to calcium pyrophosphate deposition disease Journal of Education, Health and Sport Calcium Pyrophosphate deposition disease pharmacological treatment biological medications non-pharmacological treatment criteria of CPPD diagnosis |
| title | A review on diagnosis and treatment approaches to calcium pyrophosphate deposition disease |
| title_full | A review on diagnosis and treatment approaches to calcium pyrophosphate deposition disease |
| title_fullStr | A review on diagnosis and treatment approaches to calcium pyrophosphate deposition disease |
| title_full_unstemmed | A review on diagnosis and treatment approaches to calcium pyrophosphate deposition disease |
| title_short | A review on diagnosis and treatment approaches to calcium pyrophosphate deposition disease |
| title_sort | review on diagnosis and treatment approaches to calcium pyrophosphate deposition disease |
| topic | Calcium Pyrophosphate deposition disease pharmacological treatment biological medications non-pharmacological treatment criteria of CPPD diagnosis |
| url | https://apcz.umk.pl/JEHS/article/view/56618 |
| work_keys_str_mv | AT negarhosseinnejad areviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT aleksandracygnarowicz areviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT anetaklaudiawojtas areviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT krystynazabojska areviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT urszulakorotko areviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT anetamandziuk areviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT kingawitowska areviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT mariolaturemka areviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT mikolajbiskupski areviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT karolinasacher areviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT negarhosseinnejad reviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT aleksandracygnarowicz reviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT anetaklaudiawojtas reviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT krystynazabojska reviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT urszulakorotko reviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT anetamandziuk reviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT kingawitowska reviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT mariolaturemka reviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT mikolajbiskupski reviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease AT karolinasacher reviewondiagnosisandtreatmentapproachestocalciumpyrophosphatedepositiondisease |