WDR75: An essential protein for ribosome assembly undergoing purifying selection.
Ribosomes, vital for life, consist of a large subunit and a small subunit (SSU), the latter is crucial for translation initiation and mRNA binding. The SSU processome, a 71-protein multimer in humans, is an intermediate in ribosome formation. One of its constituents, WDR75 plays a pivotal role by bi...
Saved in:
| Main Authors: | Lauren Lee, Justen B Whittall |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0318395 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Ribosomal Proteins in Ribosome Assembly
by: Brigitte Pertschy, et al.
Published: (2024-12-01) -
Interaction between the assembly of the ribosomal subunits: Disruption of 40S ribosomal assembly causes accumulation of extra-ribosomal 60S ribosomal protein uL18/L5.
by: Nusrat Rahman, et al.
Published: (2020-01-01) -
When a ribosomal protein grows up – the ribosome assembly path of Rps3
by: Brigitte Pertschy
Published: (2017-03-01) -
WDR55 is a nucleolar modulator of ribosomal RNA synthesis, cell cycle progression, and teleost organ development.
by: Norimasa Iwanami, et al.
Published: (2008-08-01) -
In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation
by: Michael C Jewett, et al.
Published: (2013-06-01)