Synthesis and study of biological activity of some new Imidazole derivatives
In this work ester derivatives were synthesized by the reaction of imidazole derivatives (C1) with ethylchloroacetate in ethanol and NaOH to give the corresponding (C2) .While compound (C3) acetohydrazide was synthesized by the reaction of ester derivatives (C2) with hydrazine hydrat in ethanol. Com...
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| Language: | English |
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University of Baghdad, College of Science for Women
2018-12-01
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| Series: | مجلة بغداد للعلوم |
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| Online Access: | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2939 |
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| author | Baghdad Science Journal |
| author_facet | Baghdad Science Journal |
| author_sort | Baghdad Science Journal |
| collection | DOAJ |
| description | In this work ester derivatives were synthesized by the reaction of imidazole derivatives (C1) with ethylchloroacetate in ethanol and NaOH to give the corresponding (C2) .While compound (C3) acetohydrazide was synthesized by the reaction of ester derivatives (C2) with hydrazine hydrat in ethanol. Compound (C3) from the reaction with different aromatic aldehydes in absolute ethanol gave the Schiff′s bases (C4,C5). The product compounds were characterized by FT-IR, U.V and 1HNMR spectra and the biological activities were studied as antibacterial. |
| format | Article |
| id | doaj-art-8aaca09f8b934d47a87a81fa45739fc6 |
| institution | Kabale University |
| issn | 2078-8665 2411-7986 |
| language | English |
| publishDate | 2018-12-01 |
| publisher | University of Baghdad, College of Science for Women |
| record_format | Article |
| series | مجلة بغداد للعلوم |
| spelling | doaj-art-8aaca09f8b934d47a87a81fa45739fc62025-08-20T03:34:00ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862018-12-0113310.21123/bsj.13.3.547-555Synthesis and study of biological activity of some new Imidazole derivativesBaghdad Science JournalIn this work ester derivatives were synthesized by the reaction of imidazole derivatives (C1) with ethylchloroacetate in ethanol and NaOH to give the corresponding (C2) .While compound (C3) acetohydrazide was synthesized by the reaction of ester derivatives (C2) with hydrazine hydrat in ethanol. Compound (C3) from the reaction with different aromatic aldehydes in absolute ethanol gave the Schiff′s bases (C4,C5). The product compounds were characterized by FT-IR, U.V and 1HNMR spectra and the biological activities were studied as antibacterial.http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2939acetohydrazide, Schiff′s bases, Imidazole |
| spellingShingle | Baghdad Science Journal Synthesis and study of biological activity of some new Imidazole derivatives مجلة بغداد للعلوم acetohydrazide, Schiff′s bases, Imidazole |
| title | Synthesis and study of biological activity of some new Imidazole derivatives |
| title_full | Synthesis and study of biological activity of some new Imidazole derivatives |
| title_fullStr | Synthesis and study of biological activity of some new Imidazole derivatives |
| title_full_unstemmed | Synthesis and study of biological activity of some new Imidazole derivatives |
| title_short | Synthesis and study of biological activity of some new Imidazole derivatives |
| title_sort | synthesis and study of biological activity of some new imidazole derivatives |
| topic | acetohydrazide, Schiff′s bases, Imidazole |
| url | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2939 |
| work_keys_str_mv | AT baghdadsciencejournal synthesisandstudyofbiologicalactivityofsomenewimidazolederivatives |