CYP3A5 genotyping-guided dosing versus weight-based dosing in a multi-ethnic population of kidney transplant recipients

CYP3A5 genotyping-guided dosing versus weight-based dosing in a multi-ethnic population of kidney transplant recipients

Introduction Tacrolimus is the cornerstone of immunosuppression after kidney transplantation (KTx) and is characterized by a narrow therapeutic index and large inter-individual variability. Pre-transplant CYP3A5 genotyping to guide tacrolimus dosing may help achieve target levels more rapidly and im...

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Bibliographic Details
Main Authors:	Rou Wei Lim, Quan Yao Ho, Yan Ting Yeo, Ian Tatt Liew, Carolyn Shan-Yeu Tien, Sobhana Thangaraju, Puay Hoon Lee, Terence Kee
Format:	Article
Language:	English
Published:	SAGE Publishing 2025-07-01
Series:	Proceedings of Singapore Healthcare
Online Access:	https://doi.org/10.1177/20101058251365300
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