Recurrent pregnancy loss - a life changing condition for women

Recurrent pregnancy loss (RPL) is estimated to occur in 2.5% of women trying to conceive. Definition of RPL varies depending on used guideline. In Europe, RPL is defined as two or more lost pregnancies before 24 weeks’ gestation. Although many factors have been associated with a higher risk of r...

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Main Authors: Oana Denisa Bălălău, Fernanda-Ecaterina Augustin, Delia-Maria Bogheanu, Alin-Gabriel Negulescu, Romina Marina Sima, Anca Silvia Dumitriu, Stana Paunica, Liana Pleș
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Journal of Mind and Medical Sciences
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Online Access:https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1384&context=jmms
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author Oana Denisa Bălălău
Fernanda-Ecaterina Augustin
Delia-Maria Bogheanu
Alin-Gabriel Negulescu
Romina Marina Sima
Anca Silvia Dumitriu
Stana Paunica
Liana Pleș
author_facet Oana Denisa Bălălău
Fernanda-Ecaterina Augustin
Delia-Maria Bogheanu
Alin-Gabriel Negulescu
Romina Marina Sima
Anca Silvia Dumitriu
Stana Paunica
Liana Pleș
author_sort Oana Denisa Bălălău
collection DOAJ
description Recurrent pregnancy loss (RPL) is estimated to occur in 2.5% of women trying to conceive. Definition of RPL varies depending on used guideline. In Europe, RPL is defined as two or more lost pregnancies before 24 weeks’ gestation. Although many factors have been associated with a higher risk of recurrent miscarriage, the aetiology is unknown in about half of cases. Several factors have been related to recurrent pregnancy loss, such as: environmental, behavioral, genetic, endocrine, metabolic, autoimmune, anatomic, thrombophilia and male factor. Given the multitude of etiopathogenic factors, RPL frequently requires an interdisciplinary approach for diagnosis and treatment. By its repetitive nature, RPL represents a psychological trauma on the couple who wants to conceive a child. Consequently, empathy and support are also necessary to be integrated in the therapeutic approach in the case of couples with recurrent miscarriage.
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publishDate 2023-04-01
publisher MDPI AG
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series Journal of Mind and Medical Sciences
spelling doaj-art-8a9f5ee2143147f99ae0353053576d9f2025-08-20T03:06:47ZengMDPI AGJournal of Mind and Medical Sciences2392-76742023-04-0110181410.22543/2392-7674.1384Recurrent pregnancy loss - a life changing condition for womenOana Denisa Bălălău0Fernanda-Ecaterina Augustin1Delia-Maria Bogheanu2Alin-Gabriel Negulescu3Romina Marina Sima4Anca Silvia Dumitriu5Stana Paunica6Liana Pleș7Carol Davila University of Medicine and Pharmacy, Faculty of General Medicine, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Faculty of General Medicine, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Faculty of General Medicine, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Faculty of General Medicine, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Faculty of General Medicine, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Dan Theodorescu Hospital, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Dan Theodorescu Hospital, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Faculty of General Medicine, Bucharest, RomaniaRecurrent pregnancy loss (RPL) is estimated to occur in 2.5% of women trying to conceive. Definition of RPL varies depending on used guideline. In Europe, RPL is defined as two or more lost pregnancies before 24 weeks’ gestation. Although many factors have been associated with a higher risk of recurrent miscarriage, the aetiology is unknown in about half of cases. Several factors have been related to recurrent pregnancy loss, such as: environmental, behavioral, genetic, endocrine, metabolic, autoimmune, anatomic, thrombophilia and male factor. Given the multitude of etiopathogenic factors, RPL frequently requires an interdisciplinary approach for diagnosis and treatment. By its repetitive nature, RPL represents a psychological trauma on the couple who wants to conceive a child. Consequently, empathy and support are also necessary to be integrated in the therapeutic approach in the case of couples with recurrent miscarriage.https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1384&context=jmmspregnancy lossabortionrecurrentthrombophilia
spellingShingle Oana Denisa Bălălău
Fernanda-Ecaterina Augustin
Delia-Maria Bogheanu
Alin-Gabriel Negulescu
Romina Marina Sima
Anca Silvia Dumitriu
Stana Paunica
Liana Pleș
Recurrent pregnancy loss - a life changing condition for women
Journal of Mind and Medical Sciences
pregnancy loss
abortion
recurrent
thrombophilia
title Recurrent pregnancy loss - a life changing condition for women
title_full Recurrent pregnancy loss - a life changing condition for women
title_fullStr Recurrent pregnancy loss - a life changing condition for women
title_full_unstemmed Recurrent pregnancy loss - a life changing condition for women
title_short Recurrent pregnancy loss - a life changing condition for women
title_sort recurrent pregnancy loss a life changing condition for women
topic pregnancy loss
abortion
recurrent
thrombophilia
url https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1384&context=jmms
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AT rominamarinasima recurrentpregnancylossalifechangingconditionforwomen
AT ancasilviadumitriu recurrentpregnancylossalifechangingconditionforwomen
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