Computed Tomographic Findings of Eosinophilic Enteritis in Eight Cats: Case Series

ABSTRACT In cats, eosinophilic enteritis (EE) is diagnosed when eosinophils are the predominant inflammatory cells on histopathology and no underlying trigger for their presence can be identified. Gastrointestinal eosinophilic sclerosing fibroplasia is a unique fibroblastic response of EE. Contrast‐...

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Main Authors: Toshiyuki Tanaka, Hana Tsuruta, Koudai Furukawa, Hideo Akiyoshi
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Veterinary Medicine and Science
Subjects:
Online Access:https://doi.org/10.1002/vms3.70353
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author Toshiyuki Tanaka
Hana Tsuruta
Koudai Furukawa
Hideo Akiyoshi
author_facet Toshiyuki Tanaka
Hana Tsuruta
Koudai Furukawa
Hideo Akiyoshi
author_sort Toshiyuki Tanaka
collection DOAJ
description ABSTRACT In cats, eosinophilic enteritis (EE) is diagnosed when eosinophils are the predominant inflammatory cells on histopathology and no underlying trigger for their presence can be identified. Gastrointestinal eosinophilic sclerosing fibroplasia is a unique fibroblastic response of EE. Contrast‐enhanced computed tomography (CT) facilitates the objective characterisation of intestinal lesions and associated pathology. To the best of our knowledge, there are no reports of CT findings in cats with EE. This case series retrospectively evaluated the CT findings of eight cats with EE including lesion location, intestinal wall layering structure, mass formation, location and size of lymph nodes, total wall thickness and outer intestinal layer relative thickness. The development of a layered intestinal wall appearance in the early and delayed phases was detected in seven (87.5%) and five cases (62.5%), respectively. All patients exhibited intestinal wall thickening, seven (87.5%) with marked thickening of the outer intestinal wall. Lesions were diffuse in all cats, involving the duodenum, jejunum and ileum in seven cats (87.5%) and in the ileum and colon in one cat (12.5%). Mass formation and lymphadenomegaly was detected in one (12.5%) and four cats (50%), respectively. The CT features of EE included thickening of the outer intestinal layer with development of a layered wall appearance and associated lymphadenomegaly.
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spelling doaj-art-8a9f3e7c366040a4afdd54f1ca1b41152025-08-20T03:47:58ZengWileyVeterinary Medicine and Science2053-10952025-05-01113n/an/a10.1002/vms3.70353Computed Tomographic Findings of Eosinophilic Enteritis in Eight Cats: Case SeriesToshiyuki Tanaka0Hana Tsuruta1Koudai Furukawa2Hideo Akiyoshi3Laboratory of Veterinary Advanced Diagnosis and Treatment, School of Veterinary Science Osaka Metropolitan University Osaka JapanDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine Purdue University West Lafayette Indiana USAJapan Animal Referral Medical Center Osaka Osaka JapanLaboratory of Veterinary Surgery, School of Veterinary Science Osaka Metropolitan University Osaka JapanABSTRACT In cats, eosinophilic enteritis (EE) is diagnosed when eosinophils are the predominant inflammatory cells on histopathology and no underlying trigger for their presence can be identified. Gastrointestinal eosinophilic sclerosing fibroplasia is a unique fibroblastic response of EE. Contrast‐enhanced computed tomography (CT) facilitates the objective characterisation of intestinal lesions and associated pathology. To the best of our knowledge, there are no reports of CT findings in cats with EE. This case series retrospectively evaluated the CT findings of eight cats with EE including lesion location, intestinal wall layering structure, mass formation, location and size of lymph nodes, total wall thickness and outer intestinal layer relative thickness. The development of a layered intestinal wall appearance in the early and delayed phases was detected in seven (87.5%) and five cases (62.5%), respectively. All patients exhibited intestinal wall thickening, seven (87.5%) with marked thickening of the outer intestinal wall. Lesions were diffuse in all cats, involving the duodenum, jejunum and ileum in seven cats (87.5%) and in the ileum and colon in one cat (12.5%). Mass formation and lymphadenomegaly was detected in one (12.5%) and four cats (50%), respectively. The CT features of EE included thickening of the outer intestinal layer with development of a layered wall appearance and associated lymphadenomegaly.https://doi.org/10.1002/vms3.70353colonduodenumeosinophilic enteritisfelinegastrointestinal eosinophilic sclerosing fibroplasialymphadenomegaly
spellingShingle Toshiyuki Tanaka
Hana Tsuruta
Koudai Furukawa
Hideo Akiyoshi
Computed Tomographic Findings of Eosinophilic Enteritis in Eight Cats: Case Series
Veterinary Medicine and Science
colon
duodenum
eosinophilic enteritis
feline
gastrointestinal eosinophilic sclerosing fibroplasia
lymphadenomegaly
title Computed Tomographic Findings of Eosinophilic Enteritis in Eight Cats: Case Series
title_full Computed Tomographic Findings of Eosinophilic Enteritis in Eight Cats: Case Series
title_fullStr Computed Tomographic Findings of Eosinophilic Enteritis in Eight Cats: Case Series
title_full_unstemmed Computed Tomographic Findings of Eosinophilic Enteritis in Eight Cats: Case Series
title_short Computed Tomographic Findings of Eosinophilic Enteritis in Eight Cats: Case Series
title_sort computed tomographic findings of eosinophilic enteritis in eight cats case series
topic colon
duodenum
eosinophilic enteritis
feline
gastrointestinal eosinophilic sclerosing fibroplasia
lymphadenomegaly
url https://doi.org/10.1002/vms3.70353
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AT hanatsuruta computedtomographicfindingsofeosinophilicenteritisineightcatscaseseries
AT koudaifurukawa computedtomographicfindingsofeosinophilicenteritisineightcatscaseseries
AT hideoakiyoshi computedtomographicfindingsofeosinophilicenteritisineightcatscaseseries