Promotion of nitric oxide production: mechanisms, strategies, and possibilities

Promotion of nitric oxide production: mechanisms, strategies, and possibilities

The discovery of nitric oxide (NO) and the role of endothelial cells (ECs) in its production has revolutionized medicine. NO can be produced by isoforms of NO synthases (NOS), including the neuronal (nNOS), inducible (iNOS), and endothelial isoforms (eNOS), and via the non-classical nitrate-nitrite-...

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Bibliographic Details
Main Authors: Marcos Gonzalez, Sarah Clayton, Eric Wauson, Daniel Christian, Quang-Kim Tran
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Physiology
Subjects:
nitric oxide
eNOS
endothelium
preclinical evidence
clinical trials
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1545044/full
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