Bleomycin-loaded folic acid-conjugated nanoliposomes: a novel formulation for targeted treatment of oral cancer

Bleomycin-loaded folic acid-conjugated nanoliposomes: a novel formulation for targeted treatment of oral cancer

IntroductionTargeted delivery of anticancer drugs holds great promise for enhancing therapeutic efficacy while minimizing adverse effects. The folate receptor (FR)-mediated approach offers a selective strategy to target cancer cells overexpressing FR. Bleomycin, an established antitumor antibiotic,...

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Main Authors: Elham Saberian, Janka Jenčová, Andrej Jenča, Fateme Salehipoor, Hadi Zare-Zardini, Adriána Petrášová, Peter Džupa, Meysam Ebrahimifar, Mohammadreza Allahyartorkaman, Jozef Jenča
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
nanoliposomes
folate receptor
targeted drug delivery
bleomycin
cancer therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1535793/full
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