Screening by Colonoscopy - Has the Time Arrived?

Colorectal cancer mortality may be reduced by several screening strategies - mathematical modelling suggests that mortality may be reduced by one-third in patients over the age of 40 years who undergo annual fecal occult blood testing. Similar modelling suggests that either colonoscopy or barium ene...

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Main Author: Richard H Hunt
Format: Article
Language:English
Published: Wiley 1990-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1990/939740
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author Richard H Hunt
author_facet Richard H Hunt
author_sort Richard H Hunt
collection DOAJ
description Colorectal cancer mortality may be reduced by several screening strategies - mathematical modelling suggests that mortality may be reduced by one-third in patients over the age of 40 years who undergo annual fecal occult blood testing. Similar modelling suggests that either colonoscopy or barium enema may reduce mortality by up to 85%. This paper reviews the evidence for different screening approaches for colorectal cancer, and identifies high risk groups in whom full colonoscopy has been studied. These studies include patients with first degree relatives with colorectal cancer, family cancer syndrome, prior breast, uterine or ovarian lesions, and follow-up for prior adenomatous polyps or cancer. The role of colonoscopy in the surveillance of patients with chronic total ulcerative colitis for dysplasia is also reviewed. The implications for patient management and possible clinical strategies are discussed.
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spelling doaj-art-8a9859efce884fc0b82881472def220f2025-08-20T03:37:37ZengWileyCanadian Journal of Gastroenterology0835-79001990-01-014952753210.1155/1990/939740Screening by Colonoscopy - Has the Time Arrived?Richard H HuntColorectal cancer mortality may be reduced by several screening strategies - mathematical modelling suggests that mortality may be reduced by one-third in patients over the age of 40 years who undergo annual fecal occult blood testing. Similar modelling suggests that either colonoscopy or barium enema may reduce mortality by up to 85%. This paper reviews the evidence for different screening approaches for colorectal cancer, and identifies high risk groups in whom full colonoscopy has been studied. These studies include patients with first degree relatives with colorectal cancer, family cancer syndrome, prior breast, uterine or ovarian lesions, and follow-up for prior adenomatous polyps or cancer. The role of colonoscopy in the surveillance of patients with chronic total ulcerative colitis for dysplasia is also reviewed. The implications for patient management and possible clinical strategies are discussed.http://dx.doi.org/10.1155/1990/939740
spellingShingle Richard H Hunt
Screening by Colonoscopy - Has the Time Arrived?
Canadian Journal of Gastroenterology
title Screening by Colonoscopy - Has the Time Arrived?
title_full Screening by Colonoscopy - Has the Time Arrived?
title_fullStr Screening by Colonoscopy - Has the Time Arrived?
title_full_unstemmed Screening by Colonoscopy - Has the Time Arrived?
title_short Screening by Colonoscopy - Has the Time Arrived?
title_sort screening by colonoscopy has the time arrived
url http://dx.doi.org/10.1155/1990/939740
work_keys_str_mv AT richardhhunt screeningbycolonoscopyhasthetimearrived