Arterial Stiffness in a Toddler with Neurofibromatosis Type 1 and Refractory Hypertension
Arterial hypertension is a common finding in patients with neurofibromatosis (NF) type 1. Renovascular hypertension due to renal artery stenosis or midaortic syndrome could be the underlying cause. We report the case of a 4-year-old girl with NF type 1 and midaortic syndrome whose changes in blood p...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2018/5957987 |
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| author | Stella Stabouli Euthymia Vargiami Olga Maliachova Nikoleta Printza John Dotis Maria Kyriazi Konstantinos O. Papazoglou Dimitrios Zafeiriou |
| author_facet | Stella Stabouli Euthymia Vargiami Olga Maliachova Nikoleta Printza John Dotis Maria Kyriazi Konstantinos O. Papazoglou Dimitrios Zafeiriou |
| author_sort | Stella Stabouli |
| collection | DOAJ |
| description | Arterial hypertension is a common finding in patients with neurofibromatosis (NF) type 1. Renovascular hypertension due to renal artery stenosis or midaortic syndrome could be the underlying cause. We report the case of a 4-year-old girl with NF type 1 and midaortic syndrome whose changes in blood pressure and pulse wave velocity suggested the evolution of vasculopathy, diagnosis of renovascular hypertension, and provided insights of response to treatment. Hypertension persisted after percutaneous transluminal angioplasty in the abdominal aorta, requiring escalation of antihypertensive treatment, while arterial stiffness demonstrated a mild decrease. Regular assessment of blood pressure using ambulatory blood pressure monitoring and noninvasive assessment of arterial stiffness may enhance the medical care of patients with NF type 1. |
| format | Article |
| id | doaj-art-8a97ccaebb80476da3ecaaa2509b0f58 |
| institution | DOAJ |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-8a97ccaebb80476da3ecaaa2509b0f582025-08-20T03:06:47ZengWileyCase Reports in Pediatrics2090-68032090-68112018-01-01201810.1155/2018/59579875957987Arterial Stiffness in a Toddler with Neurofibromatosis Type 1 and Refractory HypertensionStella Stabouli0Euthymia Vargiami1Olga Maliachova2Nikoleta Printza3John Dotis4Maria Kyriazi5Konstantinos O. Papazoglou6Dimitrios Zafeiriou71st Department of Pediatrics, Aristotle University Thessaloniki, Hippokration Hospital, Thessaloniki, Greece1st Department of Pediatrics, Aristotle University Thessaloniki, Hippokration Hospital, Thessaloniki, Greece1st Department of Pediatrics, Aristotle University Thessaloniki, Hippokration Hospital, Thessaloniki, Greece1st Department of Pediatrics, Aristotle University Thessaloniki, Hippokration Hospital, Thessaloniki, Greece1st Department of Pediatrics, Aristotle University Thessaloniki, Hippokration Hospital, Thessaloniki, Greece1st Department of Pediatrics, Aristotle University Thessaloniki, Hippokration Hospital, Thessaloniki, Greece5th Department of Surgery, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece1st Department of Pediatrics, Aristotle University Thessaloniki, Hippokration Hospital, Thessaloniki, GreeceArterial hypertension is a common finding in patients with neurofibromatosis (NF) type 1. Renovascular hypertension due to renal artery stenosis or midaortic syndrome could be the underlying cause. We report the case of a 4-year-old girl with NF type 1 and midaortic syndrome whose changes in blood pressure and pulse wave velocity suggested the evolution of vasculopathy, diagnosis of renovascular hypertension, and provided insights of response to treatment. Hypertension persisted after percutaneous transluminal angioplasty in the abdominal aorta, requiring escalation of antihypertensive treatment, while arterial stiffness demonstrated a mild decrease. Regular assessment of blood pressure using ambulatory blood pressure monitoring and noninvasive assessment of arterial stiffness may enhance the medical care of patients with NF type 1.http://dx.doi.org/10.1155/2018/5957987 |
| spellingShingle | Stella Stabouli Euthymia Vargiami Olga Maliachova Nikoleta Printza John Dotis Maria Kyriazi Konstantinos O. Papazoglou Dimitrios Zafeiriou Arterial Stiffness in a Toddler with Neurofibromatosis Type 1 and Refractory Hypertension Case Reports in Pediatrics |
| title | Arterial Stiffness in a Toddler with Neurofibromatosis Type 1 and Refractory Hypertension |
| title_full | Arterial Stiffness in a Toddler with Neurofibromatosis Type 1 and Refractory Hypertension |
| title_fullStr | Arterial Stiffness in a Toddler with Neurofibromatosis Type 1 and Refractory Hypertension |
| title_full_unstemmed | Arterial Stiffness in a Toddler with Neurofibromatosis Type 1 and Refractory Hypertension |
| title_short | Arterial Stiffness in a Toddler with Neurofibromatosis Type 1 and Refractory Hypertension |
| title_sort | arterial stiffness in a toddler with neurofibromatosis type 1 and refractory hypertension |
| url | http://dx.doi.org/10.1155/2018/5957987 |
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