Left Ventricular Ring-like Pattern: The Arrhythmic Tale of a Scarred Heart
Cardiac magnetic resonance (CMR) imaging provides significant advantages in the non-invasive diagnosis of cardiac diseases. An emerging phenotype is increasingly being described in CMR reports, the LGE “ring-like” pattern, which resembles a circumferential/semi-circumferential LV scar. Different con...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-07-01
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| Series: | Journal of Cardiovascular Development and Disease |
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| Online Access: | https://www.mdpi.com/2308-3425/12/7/275 |
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| author | Vanda Parisi Claudio Bergami Ferdinando Pasquale Maria Alessandra Schiavo Irene Ruotolo Naomi Fanciullo Nicolò Sini Matteo Ziacchi Mauro Biffi Raffaello Ditaranto Maddalena Graziosi Elena Biagini |
| author_facet | Vanda Parisi Claudio Bergami Ferdinando Pasquale Maria Alessandra Schiavo Irene Ruotolo Naomi Fanciullo Nicolò Sini Matteo Ziacchi Mauro Biffi Raffaello Ditaranto Maddalena Graziosi Elena Biagini |
| author_sort | Vanda Parisi |
| collection | DOAJ |
| description | Cardiac magnetic resonance (CMR) imaging provides significant advantages in the non-invasive diagnosis of cardiac diseases. An emerging phenotype is increasingly being described in CMR reports, the LGE “ring-like” pattern, which resembles a circumferential/semi-circumferential LV scar. Different conditions exhibit this fibrosis distribution, the majority of them being genetically determined and mostly involving cardiomyopathy-causative genes (desmosomal but also other non-desmosomal related genes). Furthermore, inflammatory diseases, such as myocarditis or sarcoidosis, could be responsible for LV fibrosis, potentially exhibiting an RL distribution. Given the heterogeneity of such conditions, effective patient management requires a stepwise and multiparametric diagnostic work-up that integrates clinical, instrumental, and genetic data to identify the specific aetiology and guide personalised treatments. |
| format | Article |
| id | doaj-art-8a97b4e14f814c91ab85a29dd2a2f6e0 |
| institution | DOAJ |
| issn | 2308-3425 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj-art-8a97b4e14f814c91ab85a29dd2a2f6e02025-08-20T02:45:49ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252025-07-0112727510.3390/jcdd12070275Left Ventricular Ring-like Pattern: The Arrhythmic Tale of a Scarred HeartVanda Parisi0Claudio Bergami1Ferdinando Pasquale2Maria Alessandra Schiavo3Irene Ruotolo4Naomi Fanciullo5Nicolò Sini6Matteo Ziacchi7Mauro Biffi8Raffaello Ditaranto9Maddalena Graziosi10Elena Biagini11Cardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti 9, 40138 Bologna, ItalyCardiac magnetic resonance (CMR) imaging provides significant advantages in the non-invasive diagnosis of cardiac diseases. An emerging phenotype is increasingly being described in CMR reports, the LGE “ring-like” pattern, which resembles a circumferential/semi-circumferential LV scar. Different conditions exhibit this fibrosis distribution, the majority of them being genetically determined and mostly involving cardiomyopathy-causative genes (desmosomal but also other non-desmosomal related genes). Furthermore, inflammatory diseases, such as myocarditis or sarcoidosis, could be responsible for LV fibrosis, potentially exhibiting an RL distribution. Given the heterogeneity of such conditions, effective patient management requires a stepwise and multiparametric diagnostic work-up that integrates clinical, instrumental, and genetic data to identify the specific aetiology and guide personalised treatments.https://www.mdpi.com/2308-3425/12/7/275cardiac magnetic resonanceCMRLGEscarphenotypering-like |
| spellingShingle | Vanda Parisi Claudio Bergami Ferdinando Pasquale Maria Alessandra Schiavo Irene Ruotolo Naomi Fanciullo Nicolò Sini Matteo Ziacchi Mauro Biffi Raffaello Ditaranto Maddalena Graziosi Elena Biagini Left Ventricular Ring-like Pattern: The Arrhythmic Tale of a Scarred Heart Journal of Cardiovascular Development and Disease cardiac magnetic resonance CMR LGE scar phenotype ring-like |
| title | Left Ventricular Ring-like Pattern: The Arrhythmic Tale of a Scarred Heart |
| title_full | Left Ventricular Ring-like Pattern: The Arrhythmic Tale of a Scarred Heart |
| title_fullStr | Left Ventricular Ring-like Pattern: The Arrhythmic Tale of a Scarred Heart |
| title_full_unstemmed | Left Ventricular Ring-like Pattern: The Arrhythmic Tale of a Scarred Heart |
| title_short | Left Ventricular Ring-like Pattern: The Arrhythmic Tale of a Scarred Heart |
| title_sort | left ventricular ring like pattern the arrhythmic tale of a scarred heart |
| topic | cardiac magnetic resonance CMR LGE scar phenotype ring-like |
| url | https://www.mdpi.com/2308-3425/12/7/275 |
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