Amino acid sequence assignment from single molecule peptide sequencing data using a two-stage classifier.
We present a machine learning-based interpretive framework (whatprot) for analyzing single molecule protein sequencing data produced by fluorosequencing, a recently developed proteomics technology that determines sparse amino acid sequences for many individual peptide molecules in a highly paralleli...
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| Main Authors: | Matthew Beauregard Smith, Zack Booth Simpson, Edward M Marcotte |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-05-01
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| Series: | PLoS Computational Biology |
| Online Access: | https://doi.org/10.1371/journal.pcbi.1011157 |
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