Exploring the alleviating effects of Bifidobacterium metabolite lactic acid on non-alcoholic steatohepatitis through the gut-liver axis

Exploring the alleviating effects of Bifidobacterium metabolite lactic acid on non-alcoholic steatohepatitis through the gut-liver axis

ObjectiveThis study investigates the protective effects of lactic acid, a metabolite of Bifidobacterium, on non-alcoholic fatty liver disease (NAFLD) induced by a high-sugar, high-fat diet (HFD) in mice, in the context of the gut-liver axis.MethodsA NAFLD mouse model was established using a HFD, and...

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Bibliographic Details
Main Authors: Hongmei Zhao, Juan Zhou, Lingzhi Yuan, Zhiyi Sun, Yi Liu, Xinyu Zhao, Feng Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Microbiology
Subjects:
NAFLD
Bifidobacterium
gut-liver axis
lactic acid
NLRP3 inflammasome
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1518150/full
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