Cysteine Peptidase B Regulates Leishmania mexicana Virulence through the Modulation of GP63 Expression.
Cysteine peptidases play a central role in the biology of Leishmania. In this work, we sought to further elucidate the mechanism(s) by which the cysteine peptidase CPB contributes to L. mexicana virulence and whether CPB participates in the formation of large communal parasitophorous vacuoles induce...
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| Main Authors: | Pierre-André Casgrain, Caroline Martel, W Robert McMaster, Jeremy C Mottram, Martin Olivier, Albert Descoteaux |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2016-05-01
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| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1005658 |
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