Lumbar punctures based on computerized tomography scans combined with precise calculations: a new lumbar puncture technique for spinal muscular atrophy patients with scoliosis
ObjectiveWe report our experience performing lumbar punctures using a novel technique in (Spinal muscular atrophy) SMA patients with scoliosis.MethodsA retrospective case series was conducted at the Department of Neurology at Xuzhou Central Hospital from January 2022 to August 2024. Patients diagnos...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2025.1654310/full |
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| author | Hongyuan Li Juan Du Xi Chen Hanbing Lu Yan Jiao Shuyu Dong |
| author_facet | Hongyuan Li Juan Du Xi Chen Hanbing Lu Yan Jiao Shuyu Dong |
| author_sort | Hongyuan Li |
| collection | DOAJ |
| description | ObjectiveWe report our experience performing lumbar punctures using a novel technique in (Spinal muscular atrophy) SMA patients with scoliosis.MethodsA retrospective case series was conducted at the Department of Neurology at Xuzhou Central Hospital from January 2022 to August 2024. Patients diagnosed as SMA combined with scoliosis underwent 58 lumbar punctures using a novel guidance technique. Data on first pass success rate, needling time, using of sedation and adverse events (AEs) were collected and analyzed.ResultsA total of 58 successful lumbar punctures were performed on six SMA patients with scoliosis using this novel technique. Most patients achieved first pass success for each LP, except for one patient. The media first LP needling time was 70.5 s (range: 45 s−150 s). For subsequent procedures, the needling time was shorter than for the first LP in all patients. Apart from one instance of back pain and one case of post-puncture headache, no other AEs were observed.ConclusionLumbar punctures guided by a single CT scan combined with precise calculations can be broadly and safely applied for intrathecal injection in patients with scoliosis. |
| format | Article |
| id | doaj-art-8a9185ac5b5d45cda97f1acd0bdf3f71 |
| institution | Kabale University |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj-art-8a9185ac5b5d45cda97f1acd0bdf3f712025-08-20T03:36:13ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-08-011610.3389/fneur.2025.16543101654310Lumbar punctures based on computerized tomography scans combined with precise calculations: a new lumbar puncture technique for spinal muscular atrophy patients with scoliosisHongyuan Li0Juan Du1Xi Chen2Hanbing Lu3Yan Jiao4Shuyu Dong5Department of Neurology, Xuzhou Central Hospital No. 199, Xuzhou, Jiangsu, ChinaDepartment of Neurology, Xuzhou Central Hospital No. 199, Xuzhou, Jiangsu, ChinaDepartment of Neurology, Xuzhou Central Hospital No. 199, Xuzhou, Jiangsu, ChinaDepartment of Neurology, Xuzhou Central Hospital No. 199, Xuzhou, Jiangsu, ChinaDepartment of Obstetrics and Gynecology, Xuzhou Central Hospital No. 199, Xuzhou, Jiangsu, ChinaDepartment of Neurology, Xuzhou Central Hospital No. 199, Xuzhou, Jiangsu, ChinaObjectiveWe report our experience performing lumbar punctures using a novel technique in (Spinal muscular atrophy) SMA patients with scoliosis.MethodsA retrospective case series was conducted at the Department of Neurology at Xuzhou Central Hospital from January 2022 to August 2024. Patients diagnosed as SMA combined with scoliosis underwent 58 lumbar punctures using a novel guidance technique. Data on first pass success rate, needling time, using of sedation and adverse events (AEs) were collected and analyzed.ResultsA total of 58 successful lumbar punctures were performed on six SMA patients with scoliosis using this novel technique. Most patients achieved first pass success for each LP, except for one patient. The media first LP needling time was 70.5 s (range: 45 s−150 s). For subsequent procedures, the needling time was shorter than for the first LP in all patients. Apart from one instance of back pain and one case of post-puncture headache, no other AEs were observed.ConclusionLumbar punctures guided by a single CT scan combined with precise calculations can be broadly and safely applied for intrathecal injection in patients with scoliosis.https://www.frontiersin.org/articles/10.3389/fneur.2025.1654310/fulllumbar punctureCT scanprecise calculationscoliosisspinal muscular atrophy |
| spellingShingle | Hongyuan Li Juan Du Xi Chen Hanbing Lu Yan Jiao Shuyu Dong Lumbar punctures based on computerized tomography scans combined with precise calculations: a new lumbar puncture technique for spinal muscular atrophy patients with scoliosis Frontiers in Neurology lumbar puncture CT scan precise calculation scoliosis spinal muscular atrophy |
| title | Lumbar punctures based on computerized tomography scans combined with precise calculations: a new lumbar puncture technique for spinal muscular atrophy patients with scoliosis |
| title_full | Lumbar punctures based on computerized tomography scans combined with precise calculations: a new lumbar puncture technique for spinal muscular atrophy patients with scoliosis |
| title_fullStr | Lumbar punctures based on computerized tomography scans combined with precise calculations: a new lumbar puncture technique for spinal muscular atrophy patients with scoliosis |
| title_full_unstemmed | Lumbar punctures based on computerized tomography scans combined with precise calculations: a new lumbar puncture technique for spinal muscular atrophy patients with scoliosis |
| title_short | Lumbar punctures based on computerized tomography scans combined with precise calculations: a new lumbar puncture technique for spinal muscular atrophy patients with scoliosis |
| title_sort | lumbar punctures based on computerized tomography scans combined with precise calculations a new lumbar puncture technique for spinal muscular atrophy patients with scoliosis |
| topic | lumbar puncture CT scan precise calculation scoliosis spinal muscular atrophy |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2025.1654310/full |
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