Ancillary tests for brain death

BackgroundAncillary tests are often used in the determination of death by neurologic criteria (DNC), especially when the clinical examination is inconclusive. DNC is widely accepted, as defined by the comprehensive report of the World Brain Death Project. However, there are several medical, legal, r...

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Main Authors: Shyam Duvuru, Vivek Sanker, Rajeeb Kumar Mishra, Arvind K. Sharma, Shir Lynn Lim, Nisha Baskar, Vijay K. Sharma
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Neurology
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Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2024.1491263/full
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author Shyam Duvuru
Vivek Sanker
Rajeeb Kumar Mishra
Arvind K. Sharma
Shir Lynn Lim
Nisha Baskar
Vijay K. Sharma
author_facet Shyam Duvuru
Vivek Sanker
Rajeeb Kumar Mishra
Arvind K. Sharma
Shir Lynn Lim
Nisha Baskar
Vijay K. Sharma
author_sort Shyam Duvuru
collection DOAJ
description BackgroundAncillary tests are often used in the determination of death by neurologic criteria (DNC), especially when the clinical examination is inconclusive. DNC is widely accepted, as defined by the comprehensive report of the World Brain Death Project. However, there are several medical, legal, religious, ethical, and social controversies. Accordingly, “premature” and “delayed” diagnoses of brain death attract these issues.MethodsDepending upon the availability and experience of the managing medical teams, various ancillary tests are employed for an early and supplementary diagnosis of brain death.ResultsWe describe the practicality, test performance, and utility of some of the commonly employed ancillary tests for the diagnosis of brain death in clinical practice, along with their case examples.ConclusionBrain death is a clinical diagnosis determined by history, physical examination, and adherence to recommended criteria. All ancillary investigations are used as supplementary tests with variable accuracy parameters. These ancillary tests often facilitate an early and “timely” diagnosis of brain death.
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language English
publishDate 2025-01-01
publisher Frontiers Media S.A.
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series Frontiers in Neurology
spelling doaj-art-8a7d119f83c241a8aab71b9ade1acc902025-01-07T06:47:05ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-01-011510.3389/fneur.2024.14912631491263Ancillary tests for brain deathShyam Duvuru0Vivek Sanker1Rajeeb Kumar Mishra2Arvind K. Sharma3Shir Lynn Lim4Nisha Baskar5Vijay K. Sharma6Apollo Specialty Hospital, Madurai, IndiaApollo Specialty Hospital, Madurai, IndiaNational Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, IndiaZydus Hospitals, Ahmedabad, IndiaYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeApollo Specialty Hospital, Madurai, IndiaYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeBackgroundAncillary tests are often used in the determination of death by neurologic criteria (DNC), especially when the clinical examination is inconclusive. DNC is widely accepted, as defined by the comprehensive report of the World Brain Death Project. However, there are several medical, legal, religious, ethical, and social controversies. Accordingly, “premature” and “delayed” diagnoses of brain death attract these issues.MethodsDepending upon the availability and experience of the managing medical teams, various ancillary tests are employed for an early and supplementary diagnosis of brain death.ResultsWe describe the practicality, test performance, and utility of some of the commonly employed ancillary tests for the diagnosis of brain death in clinical practice, along with their case examples.ConclusionBrain death is a clinical diagnosis determined by history, physical examination, and adherence to recommended criteria. All ancillary investigations are used as supplementary tests with variable accuracy parameters. These ancillary tests often facilitate an early and “timely” diagnosis of brain death.https://www.frontiersin.org/articles/10.3389/fneur.2024.1491263/fullbrain deathancillary testsdeath by neurologic criteriabrainstem functionscerebral circulatory arresttranscranial Doppler
spellingShingle Shyam Duvuru
Vivek Sanker
Rajeeb Kumar Mishra
Arvind K. Sharma
Shir Lynn Lim
Nisha Baskar
Vijay K. Sharma
Ancillary tests for brain death
Frontiers in Neurology
brain death
ancillary tests
death by neurologic criteria
brainstem functions
cerebral circulatory arrest
transcranial Doppler
title Ancillary tests for brain death
title_full Ancillary tests for brain death
title_fullStr Ancillary tests for brain death
title_full_unstemmed Ancillary tests for brain death
title_short Ancillary tests for brain death
title_sort ancillary tests for brain death
topic brain death
ancillary tests
death by neurologic criteria
brainstem functions
cerebral circulatory arrest
transcranial Doppler
url https://www.frontiersin.org/articles/10.3389/fneur.2024.1491263/full
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