PHYSICO-CHEMICAL PROPERTIES OF RAT PLASMA LIPOPROTEINS: INFLUENCES OF SYMPATHETIC AND PARASYMPATHETIC LIVER DENERVATION, PARTIAL HEPATECTOMY AND INTRAPORTAL INTRODUCTION OF ATROPIN
Physical-chemical properties of very low density (VLDL) and two forms of high density lipoproteins (LP) - apo E-rich HDL and apo A-rich HDL in rat blood plasma after sympathetic and parasympathetic denervation of the liver, partial hepatectomy and intraportal atropine administration were investigate...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2000-12-01
|
| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2241 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849690872915951616 |
|---|---|
| author | N. S. Parfenova A. A. Kuznetsov |
| author_facet | N. S. Parfenova A. A. Kuznetsov |
| author_sort | N. S. Parfenova |
| collection | DOAJ |
| description | Physical-chemical properties of very low density (VLDL) and two forms of high density lipoproteins (LP) - apo E-rich HDL and apo A-rich HDL in rat blood plasma after sympathetic and parasympathetic denervation of the liver, partial hepatectomy and intraportal atropine administration were investigated. Surface potential of VLDL and E-HDL in all experimental groups was significantly lower than in sham operated controls, but the most pronounced decrease was after intraportal atropine administration and in 7 days after partial hepatectomy. In A-HDL this parameter was essentially the same. VLDL and E-HDL particle radius significantly decreased after 70% hepatectomy and intraportal atropine administration, was slightly lower in 7 days after section of splanchnic nerves and vagotomy and was invariable in the case of A-HDL. VLDL and A-HDL lipid microviscosity increased after sympathetic denervation, partial hepatectomy and vagotomy. The degree of increase for VLDL under such conditions was higher than for A-HDL. As to E-HDL this parameter did not change. Percent of protein in water equipment in VLDL and E-HDL was greater after vagotomy and atropine administration and did not change in case of bilateral section of splanchnic nerves and hepatectomy. In A-HDL, this parameter was constant.As all these parameters reflect the LP assembling, structure and transformation, our results confirm the suggestion that autonomic neuronal factors influence the LP production, acting on post-transcriptional processes. |
| format | Article |
| id | doaj-art-8a795fe55b2948cfaef761566cea9e45 |
| institution | DOAJ |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2000-12-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-8a795fe55b2948cfaef761566cea9e452025-08-20T03:21:12Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202000-12-010657591993PHYSICO-CHEMICAL PROPERTIES OF RAT PLASMA LIPOPROTEINS: INFLUENCES OF SYMPATHETIC AND PARASYMPATHETIC LIVER DENERVATION, PARTIAL HEPATECTOMY AND INTRAPORTAL INTRODUCTION OF ATROPINN. S. Parfenova0A. A. Kuznetsov1Институт экспериментальной медицины РАМН, Санкт-ПетербургИнститут экспериментальной медицины РАМН, Санкт-ПетербургPhysical-chemical properties of very low density (VLDL) and two forms of high density lipoproteins (LP) - apo E-rich HDL and apo A-rich HDL in rat blood plasma after sympathetic and parasympathetic denervation of the liver, partial hepatectomy and intraportal atropine administration were investigated. Surface potential of VLDL and E-HDL in all experimental groups was significantly lower than in sham operated controls, but the most pronounced decrease was after intraportal atropine administration and in 7 days after partial hepatectomy. In A-HDL this parameter was essentially the same. VLDL and E-HDL particle radius significantly decreased after 70% hepatectomy and intraportal atropine administration, was slightly lower in 7 days after section of splanchnic nerves and vagotomy and was invariable in the case of A-HDL. VLDL and A-HDL lipid microviscosity increased after sympathetic denervation, partial hepatectomy and vagotomy. The degree of increase for VLDL under such conditions was higher than for A-HDL. As to E-HDL this parameter did not change. Percent of protein in water equipment in VLDL and E-HDL was greater after vagotomy and atropine administration and did not change in case of bilateral section of splanchnic nerves and hepatectomy. In A-HDL, this parameter was constant.As all these parameters reflect the LP assembling, structure and transformation, our results confirm the suggestion that autonomic neuronal factors influence the LP production, acting on post-transcriptional processes.https://russjcardiol.elpub.ru/jour/article/view/2241liverdenervationhepatectomyatropinelipoproteins |
| spellingShingle | N. S. Parfenova A. A. Kuznetsov PHYSICO-CHEMICAL PROPERTIES OF RAT PLASMA LIPOPROTEINS: INFLUENCES OF SYMPATHETIC AND PARASYMPATHETIC LIVER DENERVATION, PARTIAL HEPATECTOMY AND INTRAPORTAL INTRODUCTION OF ATROPIN Российский кардиологический журнал liver denervation hepatectomy atropine lipoproteins |
| title | PHYSICO-CHEMICAL PROPERTIES OF RAT PLASMA LIPOPROTEINS: INFLUENCES OF SYMPATHETIC AND PARASYMPATHETIC LIVER DENERVATION, PARTIAL HEPATECTOMY AND INTRAPORTAL INTRODUCTION OF ATROPIN |
| title_full | PHYSICO-CHEMICAL PROPERTIES OF RAT PLASMA LIPOPROTEINS: INFLUENCES OF SYMPATHETIC AND PARASYMPATHETIC LIVER DENERVATION, PARTIAL HEPATECTOMY AND INTRAPORTAL INTRODUCTION OF ATROPIN |
| title_fullStr | PHYSICO-CHEMICAL PROPERTIES OF RAT PLASMA LIPOPROTEINS: INFLUENCES OF SYMPATHETIC AND PARASYMPATHETIC LIVER DENERVATION, PARTIAL HEPATECTOMY AND INTRAPORTAL INTRODUCTION OF ATROPIN |
| title_full_unstemmed | PHYSICO-CHEMICAL PROPERTIES OF RAT PLASMA LIPOPROTEINS: INFLUENCES OF SYMPATHETIC AND PARASYMPATHETIC LIVER DENERVATION, PARTIAL HEPATECTOMY AND INTRAPORTAL INTRODUCTION OF ATROPIN |
| title_short | PHYSICO-CHEMICAL PROPERTIES OF RAT PLASMA LIPOPROTEINS: INFLUENCES OF SYMPATHETIC AND PARASYMPATHETIC LIVER DENERVATION, PARTIAL HEPATECTOMY AND INTRAPORTAL INTRODUCTION OF ATROPIN |
| title_sort | physico chemical properties of rat plasma lipoproteins influences of sympathetic and parasympathetic liver denervation partial hepatectomy and intraportal introduction of atropin |
| topic | liver denervation hepatectomy atropine lipoproteins |
| url | https://russjcardiol.elpub.ru/jour/article/view/2241 |
| work_keys_str_mv | AT nsparfenova physicochemicalpropertiesofratplasmalipoproteinsinfluencesofsympatheticandparasympatheticliverdenervationpartialhepatectomyandintraportalintroductionofatropin AT aakuznetsov physicochemicalpropertiesofratplasmalipoproteinsinfluencesofsympatheticandparasympatheticliverdenervationpartialhepatectomyandintraportalintroductionofatropin |