OPPORTUNITIES FOR EARLY OUTPATIENT DIAGNOSTICS OF OBSTRUCTIVE SLEEP DISORDERED BREATHING

Aim. To evaluate the prevalence of possible obstructive respiratory disorder during sleep in outpatients by the data from computed monitoring pulse oxymetry (CPO) and questionnaires.Material and methods. To the open one stage non-randomized comparative study, 175 patients included: 37,1% males, 62,9...

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Main Authors: V. N. Larina, T. N. Mironova, E. M. Elfimova, T. A. Alekseeva, I. V. Starostin, V. P. Sidorova, A. Yu. Litvin
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2018-06-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/793
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author V. N. Larina
T. N. Mironova
E. M. Elfimova
T. A. Alekseeva
I. V. Starostin
V. P. Sidorova
A. Yu. Litvin
author_facet V. N. Larina
T. N. Mironova
E. M. Elfimova
T. A. Alekseeva
I. V. Starostin
V. P. Sidorova
A. Yu. Litvin
author_sort V. N. Larina
collection DOAJ
description Aim. To evaluate the prevalence of possible obstructive respiratory disorder during sleep in outpatients by the data from computed monitoring pulse oxymetry (CPO) and questionnaires.Material and methods. To the open one stage non-randomized comparative study, 175 patients included: 37,1% males, 62,9% females, age 55,1±11,1 y.o., visiting a clinician office at outpatient facility. Sleep disordered breathing of obstructive origin was diagnosed with a survey, modified Stradling questionnaire and CPO; and excessive daytime sleepiness — with Epworth score. For confirmation of obstructive sleep apnea (OSA), a bifunctional monitoring was performed (BM) with further comparison of the data with CPO results.Results. Chronic hypoxemia at night by CPO was found in 71,4% patients, and probability of OSA moderate and severe — in 42,8% patients. By the modified Stradling, OSA was predicted in 57,7%, by Epworth, the daytime sleepiness was found in 11,4%. Mild OSA in BM was found in 8,9%, moderate — 14,7%, severe — 20,6%. The data from CPO matched with BM in 80% patients. Sensitivity of CPO for nocturnal hypoxemia of various severity was 92,4%, specificity — 76,4%; sensitivity of the Stradling questionnaire — 88,9%, specificity — 88,2%. Sensitivity of Epworth score — 27,8%, specificity — 82,4%.Conclusion. Chronic nocturnal hypoxemia was found in 71,4%, and probability of moderate and severe OSA — in 42,8% in outpatients with internal diseases profile. CPO and Stradling questionnaire can be applied as diagnostic instruments for OSA at outpatient stage.
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language Russian
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spelling doaj-art-8a76c764f43446d69fb1d092b2e41da12025-08-20T03:35:47Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252018-06-01173384510.15829/1728-8800-2018-3-38-45568OPPORTUNITIES FOR EARLY OUTPATIENT DIAGNOSTICS OF OBSTRUCTIVE SLEEP DISORDERED BREATHINGV. N. Larina0T. N. Mironova1E. M. Elfimova2T. A. Alekseeva3I. V. Starostin4V. P. Sidorova5A. Yu. Litvin6N. I. Pirogov Russian National Research Medical University (RNRMU) of the Ministry of HealthN. I. Pirogov Russian National Research Medical University (RNRMU) of the Ministry of HealthNational Medical Research Center of Cardiology of the Ministry of HealthNational Medical Research Center of Cardiology of the Ministry of HealthLLC “Three Generations Clinic”Diagnostic Clinical Center № 1 of MoscowN. I. Pirogov Russian National Research Medical University (RNRMU) of the Ministry of Health; National Medical Research Center of Cardiology of the Ministry of HealthAim. To evaluate the prevalence of possible obstructive respiratory disorder during sleep in outpatients by the data from computed monitoring pulse oxymetry (CPO) and questionnaires.Material and methods. To the open one stage non-randomized comparative study, 175 patients included: 37,1% males, 62,9% females, age 55,1±11,1 y.o., visiting a clinician office at outpatient facility. Sleep disordered breathing of obstructive origin was diagnosed with a survey, modified Stradling questionnaire and CPO; and excessive daytime sleepiness — with Epworth score. For confirmation of obstructive sleep apnea (OSA), a bifunctional monitoring was performed (BM) with further comparison of the data with CPO results.Results. Chronic hypoxemia at night by CPO was found in 71,4% patients, and probability of OSA moderate and severe — in 42,8% patients. By the modified Stradling, OSA was predicted in 57,7%, by Epworth, the daytime sleepiness was found in 11,4%. Mild OSA in BM was found in 8,9%, moderate — 14,7%, severe — 20,6%. The data from CPO matched with BM in 80% patients. Sensitivity of CPO for nocturnal hypoxemia of various severity was 92,4%, specificity — 76,4%; sensitivity of the Stradling questionnaire — 88,9%, specificity — 88,2%. Sensitivity of Epworth score — 27,8%, specificity — 82,4%.Conclusion. Chronic nocturnal hypoxemia was found in 71,4%, and probability of moderate and severe OSA — in 42,8% in outpatients with internal diseases profile. CPO and Stradling questionnaire can be applied as diagnostic instruments for OSA at outpatient stage.https://cardiovascular.elpub.ru/jour/article/view/793nocturnal hypoxemiacomputed pulse oximetrybifunctional monitoringsleep disordered breathing
spellingShingle V. N. Larina
T. N. Mironova
E. M. Elfimova
T. A. Alekseeva
I. V. Starostin
V. P. Sidorova
A. Yu. Litvin
OPPORTUNITIES FOR EARLY OUTPATIENT DIAGNOSTICS OF OBSTRUCTIVE SLEEP DISORDERED BREATHING
Кардиоваскулярная терапия и профилактика
nocturnal hypoxemia
computed pulse oximetry
bifunctional monitoring
sleep disordered breathing
title OPPORTUNITIES FOR EARLY OUTPATIENT DIAGNOSTICS OF OBSTRUCTIVE SLEEP DISORDERED BREATHING
title_full OPPORTUNITIES FOR EARLY OUTPATIENT DIAGNOSTICS OF OBSTRUCTIVE SLEEP DISORDERED BREATHING
title_fullStr OPPORTUNITIES FOR EARLY OUTPATIENT DIAGNOSTICS OF OBSTRUCTIVE SLEEP DISORDERED BREATHING
title_full_unstemmed OPPORTUNITIES FOR EARLY OUTPATIENT DIAGNOSTICS OF OBSTRUCTIVE SLEEP DISORDERED BREATHING
title_short OPPORTUNITIES FOR EARLY OUTPATIENT DIAGNOSTICS OF OBSTRUCTIVE SLEEP DISORDERED BREATHING
title_sort opportunities for early outpatient diagnostics of obstructive sleep disordered breathing
topic nocturnal hypoxemia
computed pulse oximetry
bifunctional monitoring
sleep disordered breathing
url https://cardiovascular.elpub.ru/jour/article/view/793
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