Hypocaloric diet in thrombosis risk reduction among patients with arterial hypertension and metabolic syndrome
The aim of the study was to assess hypocaloric diet effects on platelet aggregation and their mechanisms in patients with arterial hypertension (AH), android obesity (AO), and impaired glucose tolerance (IGT). In total, 25 middle;aged patients with AH, AO and IGT were examined. Anthropometry, assess...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2006-02-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/1694 |
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| _version_ | 1849249953048690688 |
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| author | I. N. Medvedev |
| author_facet | I. N. Medvedev |
| author_sort | I. N. Medvedev |
| collection | DOAJ |
| description | The aim of the study was to assess hypocaloric diet effects on platelet aggregation and their mechanisms in patients with arterial hypertension (AH), android obesity (AO), and impaired glucose tolerance (IGT). In total, 25 middle;aged patients with AH, AO and IGT were examined. Anthropometry, assessment of lipid profile, plasma and platelet lipid peroxidation, and platelet hemostasis were performed. All participants received hypocaloric diet for 24 weeks. In patients with AH, AO and IGT, hypocaloric diet improved lipid profile, suppressed peroxidation syndrome, beneficial; ly influenced intra;platelet aggregation mechanisms. Hypocaloric diet also decreased in vitro platelet adhesion and aggrega;tion, especially by the end of 24;week intervention, even though control levels were not achieved. Conclusion. For adequate correction of metabolism and platelet hemostasis in patients with AH, AO and IGT, isolated administration of hypocaloric diet is not enough. Other therapeutic approaches are needed for individuals with AH, AO and IGT. |
| format | Article |
| id | doaj-art-8a717796ec284130b7f05fbc29751a60 |
| institution | Kabale University |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2006-02-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-8a717796ec284130b7f05fbc29751a602025-08-20T03:57:25Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202006-02-010127321460Hypocaloric diet in thrombosis risk reduction among patients with arterial hypertension and metabolic syndromeI. N. Medvedev0Курский институт социального образования (филиал) РГСУThe aim of the study was to assess hypocaloric diet effects on platelet aggregation and their mechanisms in patients with arterial hypertension (AH), android obesity (AO), and impaired glucose tolerance (IGT). In total, 25 middle;aged patients with AH, AO and IGT were examined. Anthropometry, assessment of lipid profile, plasma and platelet lipid peroxidation, and platelet hemostasis were performed. All participants received hypocaloric diet for 24 weeks. In patients with AH, AO and IGT, hypocaloric diet improved lipid profile, suppressed peroxidation syndrome, beneficial; ly influenced intra;platelet aggregation mechanisms. Hypocaloric diet also decreased in vitro platelet adhesion and aggrega;tion, especially by the end of 24;week intervention, even though control levels were not achieved. Conclusion. For adequate correction of metabolism and platelet hemostasis in patients with AH, AO and IGT, isolated administration of hypocaloric diet is not enough. Other therapeutic approaches are needed for individuals with AH, AO and IGT.https://russjcardiol.elpub.ru/jour/article/view/1694arterial hypertensionabdominal obesityimpaired glucose toleranceplateletshypocaloric diet |
| spellingShingle | I. N. Medvedev Hypocaloric diet in thrombosis risk reduction among patients with arterial hypertension and metabolic syndrome Российский кардиологический журнал arterial hypertension abdominal obesity impaired glucose tolerance platelets hypocaloric diet |
| title | Hypocaloric diet in thrombosis risk reduction among patients with arterial hypertension and metabolic syndrome |
| title_full | Hypocaloric diet in thrombosis risk reduction among patients with arterial hypertension and metabolic syndrome |
| title_fullStr | Hypocaloric diet in thrombosis risk reduction among patients with arterial hypertension and metabolic syndrome |
| title_full_unstemmed | Hypocaloric diet in thrombosis risk reduction among patients with arterial hypertension and metabolic syndrome |
| title_short | Hypocaloric diet in thrombosis risk reduction among patients with arterial hypertension and metabolic syndrome |
| title_sort | hypocaloric diet in thrombosis risk reduction among patients with arterial hypertension and metabolic syndrome |
| topic | arterial hypertension abdominal obesity impaired glucose tolerance platelets hypocaloric diet |
| url | https://russjcardiol.elpub.ru/jour/article/view/1694 |
| work_keys_str_mv | AT inmedvedev hypocaloricdietinthrombosisriskreductionamongpatientswitharterialhypertensionandmetabolicsyndrome |