Effect of Hematopoietic Stem Cell Transplantation Regimen on Tacrolimus Pharmacokinetics

Effect of Hematopoietic Stem Cell Transplantation Regimen on Tacrolimus Pharmacokinetics

ABSTRACT: Objectives: Treatment with tacrolimus requires strict control of the whole-blood concentration in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT). In patients undergoing cord blood transplantation (CBT), there is a negative correlation between volume of distr...

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Main Authors: Haruno Oku, BS, Saki Yoshida, BS, Takumi Hotta, BS, Hirohito Muroi, BS, Keizo Fukushima, PhD, Kei Irie, PhD, Tatsuya Hirano, BS, Yoshimitsu Shimomura, MD, Takayuki Ishikawa, MD, PhD, Hiroaki Ikesue, PhD, Nobuyuki Muroi, PhD, Tohru Hashida, PhD, Nobuyuki Sugioka, PhD
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Therapeutic Research
Subjects:
hematopoietic stem cell transplantation
population pharmacokinetics
tacrolimus
therapeutic drug monitoring
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X24000456
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