Childhood Posterior Reversible Encephalopathy Syndrome (PRES) in Resource Limited Settings: Addressing Diagnostic and Therapeutic Hurdles-A Case Report
Posterior reversible encephalopathy syndrome (PRES) is a condition that manifests with symptoms like altered mental status, seizures, vision impairment, and vasogenic edema primarily affecting the occipital and parietal lobes, with occasional involvement of the frontoparietal regions. We report a ca...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/crpe/9444554 |
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| author | Bipesh Kumar Shah Sadmarg Thakur Prajjwol Luitel Roshan Gaire |
| author_facet | Bipesh Kumar Shah Sadmarg Thakur Prajjwol Luitel Roshan Gaire |
| author_sort | Bipesh Kumar Shah |
| collection | DOAJ |
| description | Posterior reversible encephalopathy syndrome (PRES) is a condition that manifests with symptoms like altered mental status, seizures, vision impairment, and vasogenic edema primarily affecting the occipital and parietal lobes, with occasional involvement of the frontoparietal regions. We report a case of a 10 year old girl who arrived at the pediatric emergency department with generalized swelling, dark-colored urine, and two days of seizures following recent throat infection. Her blood pressure consistently exceeded the 95th percentile by +12 mm Hg, indicating stage 2 hypertension. A computed tomography (CT) scan showed hypodensities (edema) in the parieto-occipital white matter, consistent with PRES. Due to limited resources, magnetic resonance imaging (MRI) could not be performed. The patient was treated symptomatically with levetiracetam for seizures and furosemide and amlodipine for hypertension. By the fifth day of hospitalization, the patient experienced significant improvement, with a return to normal appetite, urine color, and neurological function. Early diagnosis contributed to her full recovery. Physicians in resource limited settings should have high degree of suspicion of pediatric PRES and perform detailed history taking, examination, laboratory investigations and imaging (whenever available) for management of pediatric PRES. |
| format | Article |
| id | doaj-art-8a671cb967dc4afc889f6217100cc217 |
| institution | OA Journals |
| issn | 2090-6811 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-8a671cb967dc4afc889f6217100cc2172025-08-20T01:51:46ZengWileyCase Reports in Pediatrics2090-68112025-01-01202510.1155/crpe/9444554Childhood Posterior Reversible Encephalopathy Syndrome (PRES) in Resource Limited Settings: Addressing Diagnostic and Therapeutic Hurdles-A Case ReportBipesh Kumar Shah0Sadmarg Thakur1Prajjwol Luitel2Roshan Gaire3Department of PediatricsTribhuvan University Teaching HospitalTribhuvan University Teaching HospitalTribhuvan University Teaching HospitalPosterior reversible encephalopathy syndrome (PRES) is a condition that manifests with symptoms like altered mental status, seizures, vision impairment, and vasogenic edema primarily affecting the occipital and parietal lobes, with occasional involvement of the frontoparietal regions. We report a case of a 10 year old girl who arrived at the pediatric emergency department with generalized swelling, dark-colored urine, and two days of seizures following recent throat infection. Her blood pressure consistently exceeded the 95th percentile by +12 mm Hg, indicating stage 2 hypertension. A computed tomography (CT) scan showed hypodensities (edema) in the parieto-occipital white matter, consistent with PRES. Due to limited resources, magnetic resonance imaging (MRI) could not be performed. The patient was treated symptomatically with levetiracetam for seizures and furosemide and amlodipine for hypertension. By the fifth day of hospitalization, the patient experienced significant improvement, with a return to normal appetite, urine color, and neurological function. Early diagnosis contributed to her full recovery. Physicians in resource limited settings should have high degree of suspicion of pediatric PRES and perform detailed history taking, examination, laboratory investigations and imaging (whenever available) for management of pediatric PRES.http://dx.doi.org/10.1155/crpe/9444554 |
| spellingShingle | Bipesh Kumar Shah Sadmarg Thakur Prajjwol Luitel Roshan Gaire Childhood Posterior Reversible Encephalopathy Syndrome (PRES) in Resource Limited Settings: Addressing Diagnostic and Therapeutic Hurdles-A Case Report Case Reports in Pediatrics |
| title | Childhood Posterior Reversible Encephalopathy Syndrome (PRES) in Resource Limited Settings: Addressing Diagnostic and Therapeutic Hurdles-A Case Report |
| title_full | Childhood Posterior Reversible Encephalopathy Syndrome (PRES) in Resource Limited Settings: Addressing Diagnostic and Therapeutic Hurdles-A Case Report |
| title_fullStr | Childhood Posterior Reversible Encephalopathy Syndrome (PRES) in Resource Limited Settings: Addressing Diagnostic and Therapeutic Hurdles-A Case Report |
| title_full_unstemmed | Childhood Posterior Reversible Encephalopathy Syndrome (PRES) in Resource Limited Settings: Addressing Diagnostic and Therapeutic Hurdles-A Case Report |
| title_short | Childhood Posterior Reversible Encephalopathy Syndrome (PRES) in Resource Limited Settings: Addressing Diagnostic and Therapeutic Hurdles-A Case Report |
| title_sort | childhood posterior reversible encephalopathy syndrome pres in resource limited settings addressing diagnostic and therapeutic hurdles a case report |
| url | http://dx.doi.org/10.1155/crpe/9444554 |
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