Factors associated with pregnant women’s willingness to receive maternal pertussis vaccination in Guizhou Province, China: An exploratory cross-sectional study

The rise in pertussis incidence among infants in Guizhou, China underscores the need for maternal acellular pertussis vaccine (aP) immunization, a key strategy in protecting infants from severe health consequences. However, the willingness of pregnant women in Guizhou to receive this vaccine is not...

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Main Authors: Feng Jiang, Xingui Ye, Ying Wang, Ning Tang, Jun Feng, Yuanxue Gao, Meiling Bao
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Human Vaccines & Immunotherapeutics
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Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2024.2331870
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author Feng Jiang
Xingui Ye
Ying Wang
Ning Tang
Jun Feng
Yuanxue Gao
Meiling Bao
author_facet Feng Jiang
Xingui Ye
Ying Wang
Ning Tang
Jun Feng
Yuanxue Gao
Meiling Bao
author_sort Feng Jiang
collection DOAJ
description The rise in pertussis incidence among infants in Guizhou, China underscores the need for maternal acellular pertussis vaccine (aP) immunization, a key strategy in protecting infants from severe health consequences. However, the willingness of pregnant women in Guizhou to receive this vaccine is not well-understood. This study aimed to explore pregnant women’s intentions toward maternal pertussis vaccination in Guizhou and identify the associated factors. A questionnaire based on the health belief model, was administered in an exploratory cross-sectional study from January to February 2022. Data from 564 participants were collected and analyzed. The chi-square test, Mann-Whitney U test, and Poisson regression were used to identify potential factors associated with vaccination intentions. Participants’ median age was 27 y (interquartile range (IQR): 24–31), and the median number of children per participant was one. The study found that only 36.0% of the participants intended to receive the aP vaccine while 64.0% were uncertain or negative in this regard. Significant factors associated with intentions to vaccinate included perceived barriers and cues for action and perceived benefits. The major barriers for low vaccination intentions were safety concerns for both the fetus and the mother, and family members’ negative attitudes. Free vaccines, perceiving preventive benefits, observing other pregnant women getting vaccinated, and healthcare provider recommendations may facilitate vaccination intentions. Multiple immune strategies should be developed or optimized to cope with the resurgence of pertussis.
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spelling doaj-art-8a65479bb9e74fc4a7cc1b36fd4ceea82025-08-20T02:34:20ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2024-12-0120110.1080/21645515.2024.2331870Factors associated with pregnant women’s willingness to receive maternal pertussis vaccination in Guizhou Province, China: An exploratory cross-sectional studyFeng Jiang0Xingui Ye1Ying Wang2Ning Tang3Jun Feng4Yuanxue Gao5Meiling Bao6Institute of Expanded Programme on Immunization, Guizhou Provincial Center for Disease Control and Prevention, Guiyang, ChinaInstitute of Expanded Programme on Immunization, Guizhou Provincial Center for Disease Control and Prevention, Guiyang, ChinaSchool of Public Health, Fudan University, Shanghai, ChinaInstitute of Expanded Programme on Immunization, Guizhou Provincial Center for Disease Control and Prevention, Guiyang, ChinaInstitute of Expanded Programme on Immunization, Guizhou Provincial Center for Disease Control and Prevention, Guiyang, ChinaInstitute of Expanded Programme on Immunization, Guizhou Provincial Center for Disease Control and Prevention, Guiyang, ChinaSchool of Public Health, Guizhou Medical University, Guiyang, ChinaThe rise in pertussis incidence among infants in Guizhou, China underscores the need for maternal acellular pertussis vaccine (aP) immunization, a key strategy in protecting infants from severe health consequences. However, the willingness of pregnant women in Guizhou to receive this vaccine is not well-understood. This study aimed to explore pregnant women’s intentions toward maternal pertussis vaccination in Guizhou and identify the associated factors. A questionnaire based on the health belief model, was administered in an exploratory cross-sectional study from January to February 2022. Data from 564 participants were collected and analyzed. The chi-square test, Mann-Whitney U test, and Poisson regression were used to identify potential factors associated with vaccination intentions. Participants’ median age was 27 y (interquartile range (IQR): 24–31), and the median number of children per participant was one. The study found that only 36.0% of the participants intended to receive the aP vaccine while 64.0% were uncertain or negative in this regard. Significant factors associated with intentions to vaccinate included perceived barriers and cues for action and perceived benefits. The major barriers for low vaccination intentions were safety concerns for both the fetus and the mother, and family members’ negative attitudes. Free vaccines, perceiving preventive benefits, observing other pregnant women getting vaccinated, and healthcare provider recommendations may facilitate vaccination intentions. Multiple immune strategies should be developed or optimized to cope with the resurgence of pertussis.https://www.tandfonline.com/doi/10.1080/21645515.2024.2331870Pertussis vaccinepregnant womenwillingnessintentionhealth belief modelassociated factors
spellingShingle Feng Jiang
Xingui Ye
Ying Wang
Ning Tang
Jun Feng
Yuanxue Gao
Meiling Bao
Factors associated with pregnant women’s willingness to receive maternal pertussis vaccination in Guizhou Province, China: An exploratory cross-sectional study
Human Vaccines & Immunotherapeutics
Pertussis vaccine
pregnant women
willingness
intention
health belief model
associated factors
title Factors associated with pregnant women’s willingness to receive maternal pertussis vaccination in Guizhou Province, China: An exploratory cross-sectional study
title_full Factors associated with pregnant women’s willingness to receive maternal pertussis vaccination in Guizhou Province, China: An exploratory cross-sectional study
title_fullStr Factors associated with pregnant women’s willingness to receive maternal pertussis vaccination in Guizhou Province, China: An exploratory cross-sectional study
title_full_unstemmed Factors associated with pregnant women’s willingness to receive maternal pertussis vaccination in Guizhou Province, China: An exploratory cross-sectional study
title_short Factors associated with pregnant women’s willingness to receive maternal pertussis vaccination in Guizhou Province, China: An exploratory cross-sectional study
title_sort factors associated with pregnant women s willingness to receive maternal pertussis vaccination in guizhou province china an exploratory cross sectional study
topic Pertussis vaccine
pregnant women
willingness
intention
health belief model
associated factors
url https://www.tandfonline.com/doi/10.1080/21645515.2024.2331870
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