A review of the carcinogenic potential of human papillomavirus (HPV) in urological cancers
Abstract Direct skin-to-skin contact during intimate sexual contact with a human papillomavirus (HPV)-positive individual is often the cause of HPV infection. In addition, many studies have been written up to date that look at the role of HPV in the growth of other types of tumors. Not all urologica...
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| Format: | Article |
| Language: | English |
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BMC
2025-02-01
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| Series: | Virology Journal |
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| Online Access: | https://doi.org/10.1186/s12985-025-02682-1 |
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| author | Ehsan Zolfi Farhood Khaleghi Mehr Nikoo Emtiazi Yasaman Moradi |
| author_facet | Ehsan Zolfi Farhood Khaleghi Mehr Nikoo Emtiazi Yasaman Moradi |
| author_sort | Ehsan Zolfi |
| collection | DOAJ |
| description | Abstract Direct skin-to-skin contact during intimate sexual contact with a human papillomavirus (HPV)-positive individual is often the cause of HPV infection. In addition, many studies have been written up to date that look at the role of HPV in the growth of other types of tumors. Not all urological cancers are associated with HPV. However, penile cancer (PC) is often caused by HPV, especially high-risk types. HPV-16 has been the most frequent (68.3%), followed by HPV-6 (8.1%) and HPV-18 (6.9%). An increased risk of getting certain types of urinary cancers like prostate, bladder, testicular, and kidney has also been linked to these infections. Additionally, HPV may play a part in continuous inflammation and cancer progression in different organs and tissues. So, making HPV vaccine programs available to more people of the male sex around the world could significantly lower the number of urinary cancers caused by HPV. The critical effects of HPV on different types of urologic cancers (UCs), such as testicular, prostate, penile, and kidney cancer, and the importance of HPV vaccination have been seen in this study. Graphical Abstract |
| format | Article |
| id | doaj-art-8a640ab73b8e4032910050521b969fea |
| institution | OA Journals |
| issn | 1743-422X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Virology Journal |
| spelling | doaj-art-8a640ab73b8e4032910050521b969fea2025-08-20T02:16:40ZengBMCVirology Journal1743-422X2025-02-0122113010.1186/s12985-025-02682-1A review of the carcinogenic potential of human papillomavirus (HPV) in urological cancersEhsan Zolfi0Farhood Khaleghi Mehr1Nikoo Emtiazi2Yasaman Moradi3Department of Urology, School of Medicine, Hasheminejad Kidney Center, Iran University of Medical SciencesDepartment of Urology, School of Medicine, Hasheminejad Kidney Center, Iran University of Medical SciencesDepartment of Pathology Medicine, Rasool Akram Hospital, School of Medicine, Iran University of Medical SciencesDepartment of Pathology, School of Medicine, Iran University of Medical SciencesAbstract Direct skin-to-skin contact during intimate sexual contact with a human papillomavirus (HPV)-positive individual is often the cause of HPV infection. In addition, many studies have been written up to date that look at the role of HPV in the growth of other types of tumors. Not all urological cancers are associated with HPV. However, penile cancer (PC) is often caused by HPV, especially high-risk types. HPV-16 has been the most frequent (68.3%), followed by HPV-6 (8.1%) and HPV-18 (6.9%). An increased risk of getting certain types of urinary cancers like prostate, bladder, testicular, and kidney has also been linked to these infections. Additionally, HPV may play a part in continuous inflammation and cancer progression in different organs and tissues. So, making HPV vaccine programs available to more people of the male sex around the world could significantly lower the number of urinary cancers caused by HPV. The critical effects of HPV on different types of urologic cancers (UCs), such as testicular, prostate, penile, and kidney cancer, and the importance of HPV vaccination have been seen in this study. Graphical Abstracthttps://doi.org/10.1186/s12985-025-02682-1Human papillomavirus (HPV)Urological cancerHPV vaccineProstate cancerPenile cancer |
| spellingShingle | Ehsan Zolfi Farhood Khaleghi Mehr Nikoo Emtiazi Yasaman Moradi A review of the carcinogenic potential of human papillomavirus (HPV) in urological cancers Virology Journal Human papillomavirus (HPV) Urological cancer HPV vaccine Prostate cancer Penile cancer |
| title | A review of the carcinogenic potential of human papillomavirus (HPV) in urological cancers |
| title_full | A review of the carcinogenic potential of human papillomavirus (HPV) in urological cancers |
| title_fullStr | A review of the carcinogenic potential of human papillomavirus (HPV) in urological cancers |
| title_full_unstemmed | A review of the carcinogenic potential of human papillomavirus (HPV) in urological cancers |
| title_short | A review of the carcinogenic potential of human papillomavirus (HPV) in urological cancers |
| title_sort | review of the carcinogenic potential of human papillomavirus hpv in urological cancers |
| topic | Human papillomavirus (HPV) Urological cancer HPV vaccine Prostate cancer Penile cancer |
| url | https://doi.org/10.1186/s12985-025-02682-1 |
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