Her2+ and b-HCG Producing Undifferentiated Gastric Adenocarcinoma

A 25-year-old Hispanic female with a history of anemia, schizoaffective disorder, and psychosis was admitted for anemia associated with fatigue, weakness, shortness of breath, night sweats, weight loss, and abdominal and lower back pain for the past two months. On routine management, she was found t...

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Main Authors: Sahar Eivaz-Mohammadi, Fernando Gonzalez-Ibarra, Waheed Abdul, Omer Tarar, Khurram Malik, Amer K. Syed
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2014/268919
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author Sahar Eivaz-Mohammadi
Fernando Gonzalez-Ibarra
Waheed Abdul
Omer Tarar
Khurram Malik
Amer K. Syed
author_facet Sahar Eivaz-Mohammadi
Fernando Gonzalez-Ibarra
Waheed Abdul
Omer Tarar
Khurram Malik
Amer K. Syed
author_sort Sahar Eivaz-Mohammadi
collection DOAJ
description A 25-year-old Hispanic female with a history of anemia, schizoaffective disorder, and psychosis was admitted for anemia associated with fatigue, weakness, shortness of breath, night sweats, weight loss, and abdominal and lower back pain for the past two months. On routine management, she was found to have a positive serum b-HCG of 80.4 (0–5 mIU/mL) but the patient denied any sexual activity in her life. During her admission, U/S of the pelvis was noncontributory. CT angiogram of the chest was significant for prominent mediastinal and hilar lymph nodes, diffusely thickened stomach suggesting gastric malignancy with multiple hypoenhancing lesions in the liver and diffuse lytic lesions in the spine and sacrum suspicious for metastatic disease. The MRI of the abdomen confirmed the CT angiogram findings. After these findings, EGD was performed which showed lesions in the antrum, body of the stomach, fundus, and cardia on the lesser curvature of the stomach body correlating with carcinoma. The biopsy was positive for Her2, b-HCG producing poorly differentiated gastric adenocarcinoma. Patient underwent one successful round of chemotherapy with Taxotene, Cisplatin, and 5-FU for Stage IV gastric adenocarcinoma.
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spelling doaj-art-8a42439c029a41e8bf6eb4818d1dc6ea2025-08-20T02:09:18ZengWileyCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/268919268919Her2+ and b-HCG Producing Undifferentiated Gastric AdenocarcinomaSahar Eivaz-Mohammadi0Fernando Gonzalez-Ibarra1Waheed Abdul2Omer Tarar3Khurram Malik4Amer K. Syed5Jersey City Medical Center, Department of Internal Medicine, 355 Grand Street, NJ 07302, USAJersey City Medical Center, Department of Internal Medicine, 355 Grand Street, NJ 07302, USASt. George’s University School of Medicine, Jersey City Medical Center, Department of Internal Medicine, 355 Grand Street, Jersey City, NJ 07302, USAJersey City Medical Center, Department of Internal Medicine, 355 Grand Street, NJ 07302, USAJersey City Medical Center, Department of Internal Medicine, 355 Grand Street, NJ 07302, USAJersey City Medical Center, 355 Grand Street, Jersey City, NJ 07302, USAA 25-year-old Hispanic female with a history of anemia, schizoaffective disorder, and psychosis was admitted for anemia associated with fatigue, weakness, shortness of breath, night sweats, weight loss, and abdominal and lower back pain for the past two months. On routine management, she was found to have a positive serum b-HCG of 80.4 (0–5 mIU/mL) but the patient denied any sexual activity in her life. During her admission, U/S of the pelvis was noncontributory. CT angiogram of the chest was significant for prominent mediastinal and hilar lymph nodes, diffusely thickened stomach suggesting gastric malignancy with multiple hypoenhancing lesions in the liver and diffuse lytic lesions in the spine and sacrum suspicious for metastatic disease. The MRI of the abdomen confirmed the CT angiogram findings. After these findings, EGD was performed which showed lesions in the antrum, body of the stomach, fundus, and cardia on the lesser curvature of the stomach body correlating with carcinoma. The biopsy was positive for Her2, b-HCG producing poorly differentiated gastric adenocarcinoma. Patient underwent one successful round of chemotherapy with Taxotene, Cisplatin, and 5-FU for Stage IV gastric adenocarcinoma.http://dx.doi.org/10.1155/2014/268919
spellingShingle Sahar Eivaz-Mohammadi
Fernando Gonzalez-Ibarra
Waheed Abdul
Omer Tarar
Khurram Malik
Amer K. Syed
Her2+ and b-HCG Producing Undifferentiated Gastric Adenocarcinoma
Case Reports in Medicine
title Her2+ and b-HCG Producing Undifferentiated Gastric Adenocarcinoma
title_full Her2+ and b-HCG Producing Undifferentiated Gastric Adenocarcinoma
title_fullStr Her2+ and b-HCG Producing Undifferentiated Gastric Adenocarcinoma
title_full_unstemmed Her2+ and b-HCG Producing Undifferentiated Gastric Adenocarcinoma
title_short Her2+ and b-HCG Producing Undifferentiated Gastric Adenocarcinoma
title_sort her2 and b hcg producing undifferentiated gastric adenocarcinoma
url http://dx.doi.org/10.1155/2014/268919
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AT waheedabdul her2andbhcgproducingundifferentiatedgastricadenocarcinoma
AT omertarar her2andbhcgproducingundifferentiatedgastricadenocarcinoma
AT khurrammalik her2andbhcgproducingundifferentiatedgastricadenocarcinoma
AT amerksyed her2andbhcgproducingundifferentiatedgastricadenocarcinoma