Unraveling the composition and function of pig gut microbiome from metagenomics

Abstract The gut microbiome plays a crucial role in intestinal maturation, metabolism, and immunoregulation, significantly influencing the host’s health and growth performance. This review highlights the use of metagenomic techniques to the composition, function, and dynamic changes of the pig gut m...

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Main Authors: Qiwu Tang, Xiaoping Yin, Guihui Wen, Zhang Luo, Lei Zhang, Shengguo Tan
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Animal Microbiome
Subjects:
Online Access:https://doi.org/10.1186/s42523-025-00419-7
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author Qiwu Tang
Xiaoping Yin
Guihui Wen
Zhang Luo
Lei Zhang
Shengguo Tan
author_facet Qiwu Tang
Xiaoping Yin
Guihui Wen
Zhang Luo
Lei Zhang
Shengguo Tan
author_sort Qiwu Tang
collection DOAJ
description Abstract The gut microbiome plays a crucial role in intestinal maturation, metabolism, and immunoregulation, significantly influencing the host’s health and growth performance. This review highlights the use of metagenomic techniques to the composition, function, and dynamic changes of the pig gut microbiota. Research has revealed that environmental and host factors, particularly diet, drive significant variations in microbial composition, which in turn shape host epigenetics through microbial components and metabolites. Furthermore, the strong correlation between the gut microbiota and host health presents opportunities for improving growth performance in the livestock industry.
format Article
id doaj-art-8a3dfcbd9ae84e07bfd4ec253ade9247
institution OA Journals
issn 2524-4671
language English
publishDate 2025-06-01
publisher BMC
record_format Article
series Animal Microbiome
spelling doaj-art-8a3dfcbd9ae84e07bfd4ec253ade92472025-08-20T02:05:42ZengBMCAnimal Microbiome2524-46712025-06-017111010.1186/s42523-025-00419-7Unraveling the composition and function of pig gut microbiome from metagenomicsQiwu Tang0Xiaoping Yin1Guihui Wen2Zhang Luo3Lei Zhang4Shengguo Tan5Hunan Biological and Electromechanical PolytechnicHunan Biological and Electromechanical PolytechnicHunan Biological and Electromechanical PolytechnicLiuyang Agricultural Development CenterPeople’s Government of Hezuoqiao TownshipHunan Biological and Electromechanical PolytechnicAbstract The gut microbiome plays a crucial role in intestinal maturation, metabolism, and immunoregulation, significantly influencing the host’s health and growth performance. This review highlights the use of metagenomic techniques to the composition, function, and dynamic changes of the pig gut microbiota. Research has revealed that environmental and host factors, particularly diet, drive significant variations in microbial composition, which in turn shape host epigenetics through microbial components and metabolites. Furthermore, the strong correlation between the gut microbiota and host health presents opportunities for improving growth performance in the livestock industry.https://doi.org/10.1186/s42523-025-00419-7PigGut MicrobiomeHost microbiotaIntestinal healthMicrobial compositionMetagenomics
spellingShingle Qiwu Tang
Xiaoping Yin
Guihui Wen
Zhang Luo
Lei Zhang
Shengguo Tan
Unraveling the composition and function of pig gut microbiome from metagenomics
Animal Microbiome
Pig
Gut Microbiome
Host microbiota
Intestinal health
Microbial composition
Metagenomics
title Unraveling the composition and function of pig gut microbiome from metagenomics
title_full Unraveling the composition and function of pig gut microbiome from metagenomics
title_fullStr Unraveling the composition and function of pig gut microbiome from metagenomics
title_full_unstemmed Unraveling the composition and function of pig gut microbiome from metagenomics
title_short Unraveling the composition and function of pig gut microbiome from metagenomics
title_sort unraveling the composition and function of pig gut microbiome from metagenomics
topic Pig
Gut Microbiome
Host microbiota
Intestinal health
Microbial composition
Metagenomics
url https://doi.org/10.1186/s42523-025-00419-7
work_keys_str_mv AT qiwutang unravelingthecompositionandfunctionofpiggutmicrobiomefrommetagenomics
AT xiaopingyin unravelingthecompositionandfunctionofpiggutmicrobiomefrommetagenomics
AT guihuiwen unravelingthecompositionandfunctionofpiggutmicrobiomefrommetagenomics
AT zhangluo unravelingthecompositionandfunctionofpiggutmicrobiomefrommetagenomics
AT leizhang unravelingthecompositionandfunctionofpiggutmicrobiomefrommetagenomics
AT shengguotan unravelingthecompositionandfunctionofpiggutmicrobiomefrommetagenomics