Volumetric assessment of fat graft retention over implant by MRI

**Background**: Autologous fat grafting (AFG) is an increasingly popular adjunct to post-mastectomy breast reconstruction as it can produce a natural cosmetic outcome and alleviate undesirable radiotherapy-associated consequences, with low surgical risk. However, graft retention rates are variable a...

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Main Authors: Emma K C Symonds, Heath Wilms, Carys Finlayson, Kathryn E Hally, Bianca Black, Sarah V Sparks, Angie Slocombe, Elizabeth R Dennett, Kirsty M Danielson, Ineke Meredith
Format: Article
Language:English
Published: Australian Society of Plastic Surgeons 2023-03-01
Series:Australasian Journal of Plastic Surgery
Online Access:https://doi.org/10.34239/ajops.70234
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author Emma K C Symonds
Heath Wilms
Carys Finlayson
Kathryn E Hally
Bianca Black
Sarah V Sparks
Angie Slocombe
Elizabeth R Dennett
Kirsty M Danielson
Ineke Meredith
author_facet Emma K C Symonds
Heath Wilms
Carys Finlayson
Kathryn E Hally
Bianca Black
Sarah V Sparks
Angie Slocombe
Elizabeth R Dennett
Kirsty M Danielson
Ineke Meredith
author_sort Emma K C Symonds
collection DOAJ
description **Background**: Autologous fat grafting (AFG) is an increasingly popular adjunct to post-mastectomy breast reconstruction as it can produce a natural cosmetic outcome and alleviate undesirable radiotherapy-associated consequences, with low surgical risk. However, graft retention rates are variable and unpredictable. In order to improve and understand what influences graft retention rates, accurate and consistent methods for the measurement of graft retention must be developed. **Methods**: Twenty patients who were undergoing AFG following a previous mastectomy were prospectively enrolled. Of these, six women suitable for immediate breast reconstruction (IBR) with implant underwent MRI pre- and three months post-AFG. **Results**: All patients had a net gain in volume at three months post-procedure with a mean of 123.6 ± 56.07cm^3^; however, the percentage retention ranged from 30.0 to 104.7 per cent. **Conclusions**: This study has demonstrated the feasibility of measuring AFG retention over implant using MRI, as well as confirming variable tissue retention rates. This is an important step forward for studies on improving overall graft survival.
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publishDate 2023-03-01
publisher Australian Society of Plastic Surgeons
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series Australasian Journal of Plastic Surgery
spelling doaj-art-8a2ff234b7c64a1da06e8107c32a8c982025-08-20T03:20:54ZengAustralian Society of Plastic SurgeonsAustralasian Journal of Plastic Surgery2209-170X2023-03-016110.34239/ajops.70234Volumetric assessment of fat graft retention over implant by MRIEmma K C SymondsHeath WilmsCarys FinlaysonKathryn E HallyBianca BlackSarah V SparksAngie SlocombeElizabeth R DennettKirsty M DanielsonIneke Meredith**Background**: Autologous fat grafting (AFG) is an increasingly popular adjunct to post-mastectomy breast reconstruction as it can produce a natural cosmetic outcome and alleviate undesirable radiotherapy-associated consequences, with low surgical risk. However, graft retention rates are variable and unpredictable. In order to improve and understand what influences graft retention rates, accurate and consistent methods for the measurement of graft retention must be developed. **Methods**: Twenty patients who were undergoing AFG following a previous mastectomy were prospectively enrolled. Of these, six women suitable for immediate breast reconstruction (IBR) with implant underwent MRI pre- and three months post-AFG. **Results**: All patients had a net gain in volume at three months post-procedure with a mean of 123.6 ± 56.07cm^3^; however, the percentage retention ranged from 30.0 to 104.7 per cent. **Conclusions**: This study has demonstrated the feasibility of measuring AFG retention over implant using MRI, as well as confirming variable tissue retention rates. This is an important step forward for studies on improving overall graft survival.https://doi.org/10.34239/ajops.70234
spellingShingle Emma K C Symonds
Heath Wilms
Carys Finlayson
Kathryn E Hally
Bianca Black
Sarah V Sparks
Angie Slocombe
Elizabeth R Dennett
Kirsty M Danielson
Ineke Meredith
Volumetric assessment of fat graft retention over implant by MRI
Australasian Journal of Plastic Surgery
title Volumetric assessment of fat graft retention over implant by MRI
title_full Volumetric assessment of fat graft retention over implant by MRI
title_fullStr Volumetric assessment of fat graft retention over implant by MRI
title_full_unstemmed Volumetric assessment of fat graft retention over implant by MRI
title_short Volumetric assessment of fat graft retention over implant by MRI
title_sort volumetric assessment of fat graft retention over implant by mri
url https://doi.org/10.34239/ajops.70234
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