Improvement of the Anticancer Efficacy of PD‐1/PD‐L1 Blockade: Advances in Molecular Mechanisms and Therapeutic Strategies

Improvement of the Anticancer Efficacy of PD‐1/PD‐L1 Blockade: Advances in Molecular Mechanisms and Therapeutic Strategies

ABSTRACT The clinical success of PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy. However, the issues of immune resistance have become increasingly prominent, representing a critical limitation in modern oncology. This phenomenon has prompted efforts to elucidate the mechanisms underlyin...

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Bibliographic Details
Main Authors: Peng Gao, Xiao Li, Zhenyu Duan, Yang Wang, Yinggang Li, Jing Wang, Kui Luo, Jie Chen
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:MedComm
Subjects:
PD‐1/PD‐L1 blockade resistance
cancer treatment
type I interferons
cGAS‐STING pathway
Online Access:https://doi.org/10.1002/mco2.70274
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