Epidemiology of Human Respiratory Viruses in Children with Acute Respiratory Tract Infections in Jinan, China
The viral etiologies of UTRIs and LTRIs in children in Jinan city were investigated between July 2009 and June 2010. Nasal and throat swabs were collected from 397 children with URTIs and bronchoalveolar lavage fluid specimens were collected from 323 children with LRTIs. RT-PCR/PCR was used to exami...
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| Format: | Article |
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Wiley
2013-01-01
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| Series: | Clinical and Developmental Immunology |
| Online Access: | http://dx.doi.org/10.1155/2013/210490 |
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| author | Yanqin Lu Shifu Wang Lehai Zhang Chao Xu Cuirong Bian Zhaoxia Wang Yanhui Ma Ke Wang Lixia Ma Chen Meng Caiyun Ni Jiabei Tong Gongchao Li Jinxiang Han |
| author_facet | Yanqin Lu Shifu Wang Lehai Zhang Chao Xu Cuirong Bian Zhaoxia Wang Yanhui Ma Ke Wang Lixia Ma Chen Meng Caiyun Ni Jiabei Tong Gongchao Li Jinxiang Han |
| author_sort | Yanqin Lu |
| collection | DOAJ |
| description | The viral etiologies of UTRIs and LTRIs in children in Jinan city were investigated between July 2009 and June 2010. Nasal and throat swabs were collected from 397 children with URTIs and bronchoalveolar lavage fluid specimens were collected from 323 children with LRTIs. RT-PCR/PCR was used to examine all samples for IFV, PIV, RSV, RV, hMPV, HBoV, CoV, ADV, RSV, and EV. Viral pathogens were detected in 47.10% of URTI samples and 66.57% samples, and the incidence of viral coinfection was 5.29% and 21.05%, respectively. IFV was the most common virus in URTIs, with a detection rate of 19.40%, followed by PIV (10.83%), RV (10.58%), and EV (6.30%). For LRTIs, PIV and RV were both detected in 27% of samples, followed by RSV (9.91%), HBoV (8.36%), IFV (5.57%), and hMPV (5.57%). RSV and HBoV were more prevalent in the youngest children of no more than six months. Meanwhile, RV, PIV, and RSV were the most frequent viruses combined with bacterial pathogens in LRTIs. In conclusion, the spectrum of respiratory virus infections in URTIs and LRTIs differed in terms of the most common pathogens, seasonal distribution, and coinfection rate. |
| format | Article |
| id | doaj-art-8a0e3a30ecae4cd280da6050296d493f |
| institution | Kabale University |
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| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
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| series | Clinical and Developmental Immunology |
| spelling | doaj-art-8a0e3a30ecae4cd280da6050296d493f2025-02-03T01:27:39ZengWileyClinical and Developmental Immunology1740-25221740-25302013-01-01201310.1155/2013/210490210490Epidemiology of Human Respiratory Viruses in Children with Acute Respiratory Tract Infections in Jinan, ChinaYanqin Lu0Shifu Wang1Lehai Zhang2Chao Xu3Cuirong Bian4Zhaoxia Wang5Yanhui Ma6Ke Wang7Lixia Ma8Chen Meng9Caiyun Ni10Jiabei Tong11Gongchao Li12Jinxiang Han13Shandong Medicinal Biotechnology Centre, Key Laboratory for Modern Medicine and Technology of Shandong Province, Key Laboratory for Virology of Shandong Province, Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Key Laboratory for Biotech-Drugs, Ministry of Health, Shandong Academy of Medical Sciences, No. 18877 Jingshi Road, Jinan 250062, ChinaDepartment of Laboratory, Qilu Children’s Hospital of Shandong University, Jinan 250022, ChinaDepartment of Laboratory, Qilu Children’s Hospital of Shandong University, Jinan 250022, ChinaShandong Medicinal Biotechnology Centre, Key Laboratory for Modern Medicine and Technology of Shandong Province, Key Laboratory for Virology of Shandong Province, Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Key Laboratory for Biotech-Drugs, Ministry of Health, Shandong Academy of Medical Sciences, No. 18877 Jingshi Road, Jinan 250062, ChinaSchool of Dental Medicine, Shandong University, Jinan 250012, ChinaInstitute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan 250062, ChinaRespiratory Department, Qilu Children’s Hospital of Shandong University, Jinan 250022, ChinaShandong Medicinal Biotechnology Centre, Key Laboratory for Modern Medicine and Technology of Shandong Province, Key Laboratory for Virology of Shandong Province, Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Key Laboratory for Biotech-Drugs, Ministry of Health, Shandong Academy of Medical Sciences, No. 18877 Jingshi Road, Jinan 250062, ChinaRespiratory Department, Qilu Children’s Hospital of Shandong University, Jinan 250022, ChinaRespiratory Department, Qilu Children’s Hospital of Shandong University, Jinan 250022, ChinaRespiratory Department, Qilu Children’s Hospital of Shandong University, Jinan 250022, ChinaShandong Medicinal Biotechnology Centre, Key Laboratory for Modern Medicine and Technology of Shandong Province, Key Laboratory for Virology of Shandong Province, Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Key Laboratory for Biotech-Drugs, Ministry of Health, Shandong Academy of Medical Sciences, No. 18877 Jingshi Road, Jinan 250062, ChinaShandong Medicinal Biotechnology Centre, Key Laboratory for Modern Medicine and Technology of Shandong Province, Key Laboratory for Virology of Shandong Province, Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Key Laboratory for Biotech-Drugs, Ministry of Health, Shandong Academy of Medical Sciences, No. 18877 Jingshi Road, Jinan 250062, ChinaShandong Medicinal Biotechnology Centre, Key Laboratory for Modern Medicine and Technology of Shandong Province, Key Laboratory for Virology of Shandong Province, Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Key Laboratory for Biotech-Drugs, Ministry of Health, Shandong Academy of Medical Sciences, No. 18877 Jingshi Road, Jinan 250062, ChinaThe viral etiologies of UTRIs and LTRIs in children in Jinan city were investigated between July 2009 and June 2010. Nasal and throat swabs were collected from 397 children with URTIs and bronchoalveolar lavage fluid specimens were collected from 323 children with LRTIs. RT-PCR/PCR was used to examine all samples for IFV, PIV, RSV, RV, hMPV, HBoV, CoV, ADV, RSV, and EV. Viral pathogens were detected in 47.10% of URTI samples and 66.57% samples, and the incidence of viral coinfection was 5.29% and 21.05%, respectively. IFV was the most common virus in URTIs, with a detection rate of 19.40%, followed by PIV (10.83%), RV (10.58%), and EV (6.30%). For LRTIs, PIV and RV were both detected in 27% of samples, followed by RSV (9.91%), HBoV (8.36%), IFV (5.57%), and hMPV (5.57%). RSV and HBoV were more prevalent in the youngest children of no more than six months. Meanwhile, RV, PIV, and RSV were the most frequent viruses combined with bacterial pathogens in LRTIs. In conclusion, the spectrum of respiratory virus infections in URTIs and LRTIs differed in terms of the most common pathogens, seasonal distribution, and coinfection rate.http://dx.doi.org/10.1155/2013/210490 |
| spellingShingle | Yanqin Lu Shifu Wang Lehai Zhang Chao Xu Cuirong Bian Zhaoxia Wang Yanhui Ma Ke Wang Lixia Ma Chen Meng Caiyun Ni Jiabei Tong Gongchao Li Jinxiang Han Epidemiology of Human Respiratory Viruses in Children with Acute Respiratory Tract Infections in Jinan, China Clinical and Developmental Immunology |
| title | Epidemiology of Human Respiratory Viruses in Children with Acute Respiratory Tract Infections in Jinan, China |
| title_full | Epidemiology of Human Respiratory Viruses in Children with Acute Respiratory Tract Infections in Jinan, China |
| title_fullStr | Epidemiology of Human Respiratory Viruses in Children with Acute Respiratory Tract Infections in Jinan, China |
| title_full_unstemmed | Epidemiology of Human Respiratory Viruses in Children with Acute Respiratory Tract Infections in Jinan, China |
| title_short | Epidemiology of Human Respiratory Viruses in Children with Acute Respiratory Tract Infections in Jinan, China |
| title_sort | epidemiology of human respiratory viruses in children with acute respiratory tract infections in jinan china |
| url | http://dx.doi.org/10.1155/2013/210490 |
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