Hepatotoxicity Associated with Use of the Weight Loss Supplement Garcinia cambogia: A Case Report and Review of the Literature

The use of herbal and dietary supplements for weight loss is becoming increasingly common as obesity is becoming major health problem in the United States. Despite the popularity of these natural supplements, there are no guidelines for their therapeutic doses and their safety is always a concern. G...

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Main Authors: Jiten P. Kothadia, Monica Kaminski, Hrishikesh Samant, Marco Olivera-Martinez
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Hepatology
Online Access:http://dx.doi.org/10.1155/2018/6483605
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author Jiten P. Kothadia
Monica Kaminski
Hrishikesh Samant
Marco Olivera-Martinez
author_facet Jiten P. Kothadia
Monica Kaminski
Hrishikesh Samant
Marco Olivera-Martinez
author_sort Jiten P. Kothadia
collection DOAJ
description The use of herbal and dietary supplements for weight loss is becoming increasingly common as obesity is becoming major health problem in the United States. Despite the popularity of these natural supplements, there are no guidelines for their therapeutic doses and their safety is always a concern. Garcinia cambogia extract with its active ingredient “hydroxycitric acid” is a component of many weight loss regimens. It suppresses fatty acid biosynthesis and decreases appetite. However, its prolonged use in weight maintenance is unknown. Here we describe a case of acute hepatitis after the use of Garcinia cambogia for weight loss.
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publishDate 2018-01-01
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series Case Reports in Hepatology
spelling doaj-art-8a07d7bd1c3d4139a290fdb33b9c934b2025-08-20T02:09:15ZengWileyCase Reports in Hepatology2090-65872090-65952018-01-01201810.1155/2018/64836056483605Hepatotoxicity Associated with Use of the Weight Loss Supplement Garcinia cambogia: A Case Report and Review of the LiteratureJiten P. Kothadia0Monica Kaminski1Hrishikesh Samant2Marco Olivera-Martinez3Nazih Zuhdi Transplant Institute, INTEGRIS Baptist Medical Center, 3300 NW Expressway, Oklahoma City, OK 73112, USADepartment of Internal Medicine, Coney Island Hospital, 2601 Coney Island Avenue, Brooklyn, NY 11235, USADivision of Gastroenterology and Hepatology, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USADepartment of Gastroenterology and Hepatology, University of Nebraska Medical Center, 982000 Nebraska Medical Center, Omaha, NE 68198, USAThe use of herbal and dietary supplements for weight loss is becoming increasingly common as obesity is becoming major health problem in the United States. Despite the popularity of these natural supplements, there are no guidelines for their therapeutic doses and their safety is always a concern. Garcinia cambogia extract with its active ingredient “hydroxycitric acid” is a component of many weight loss regimens. It suppresses fatty acid biosynthesis and decreases appetite. However, its prolonged use in weight maintenance is unknown. Here we describe a case of acute hepatitis after the use of Garcinia cambogia for weight loss.http://dx.doi.org/10.1155/2018/6483605
spellingShingle Jiten P. Kothadia
Monica Kaminski
Hrishikesh Samant
Marco Olivera-Martinez
Hepatotoxicity Associated with Use of the Weight Loss Supplement Garcinia cambogia: A Case Report and Review of the Literature
Case Reports in Hepatology
title Hepatotoxicity Associated with Use of the Weight Loss Supplement Garcinia cambogia: A Case Report and Review of the Literature
title_full Hepatotoxicity Associated with Use of the Weight Loss Supplement Garcinia cambogia: A Case Report and Review of the Literature
title_fullStr Hepatotoxicity Associated with Use of the Weight Loss Supplement Garcinia cambogia: A Case Report and Review of the Literature
title_full_unstemmed Hepatotoxicity Associated with Use of the Weight Loss Supplement Garcinia cambogia: A Case Report and Review of the Literature
title_short Hepatotoxicity Associated with Use of the Weight Loss Supplement Garcinia cambogia: A Case Report and Review of the Literature
title_sort hepatotoxicity associated with use of the weight loss supplement garcinia cambogia a case report and review of the literature
url http://dx.doi.org/10.1155/2018/6483605
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