Effects of Flow Rate on Delivery of Bubble Continuous Positive Airway Pressure in an In Vitro Model

There has been concern over the effect of vigorous bubbling on the delivery pressure during the operation of the bubble nasal continuous positive airway pressure (CPAP) system. We investigated the relationship between intra-tubing pressure changes and flow rates in a closed bubble CPAP system in vit...

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Main Authors: Tsyr-Yuh Ho, Shan-Fu Ou, Shih-Hui Huang, Chi-Ning Lee, Luo-Ping Ger, Kai-Sheng Hsieh, Hui-Ying Cheng, Wei Yang Lee, Ken-Pen Weng
Format: Article
Language:English
Published: Elsevier 2010-08-01
Series:Pediatrics and Neonatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957210600411
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author Tsyr-Yuh Ho
Shan-Fu Ou
Shih-Hui Huang
Chi-Ning Lee
Luo-Ping Ger
Kai-Sheng Hsieh
Hui-Ying Cheng
Wei Yang Lee
Ken-Pen Weng
author_facet Tsyr-Yuh Ho
Shan-Fu Ou
Shih-Hui Huang
Chi-Ning Lee
Luo-Ping Ger
Kai-Sheng Hsieh
Hui-Ying Cheng
Wei Yang Lee
Ken-Pen Weng
author_sort Tsyr-Yuh Ho
collection DOAJ
description There has been concern over the effect of vigorous bubbling on the delivery pressure during the operation of the bubble nasal continuous positive airway pressure (CPAP) system. We investigated the relationship between intra-tubing pressure changes and flow rates in a closed bubble CPAP system in vitro. Methods: Using an experimental (in vitro) model, the distal connecting tube of the CPAP system was immersed under the water seal to a depth of 5 cm. Sixteen different flow rates, ranging from 2 L/min to 20 L/min, were tested. The procedure was repeated 10 times at each flow rate, and the intra-tubing pressure was recorded. Results: The intra-tubing pressure within the model increased as the air flow rates were adjusted from 2 L/min to 20 L/min. The relationship was represented by the following equation, pressure (cmH2O) = 5.37 + 0.15 × flow rate (L/min) (R2 = 0.826, p < 0.001). Conclusion: These results demonstrated that the intra-tubing pressure in a bubble CPAP system was highly correlated with flow rate in vitro.
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spelling doaj-art-8a07ce7bd1db41f790bf6c2e819ac83f2025-08-20T01:55:40ZengElsevierPediatrics and Neonatology1875-95722010-08-0151421421810.1016/S1875-9572(10)60041-1Effects of Flow Rate on Delivery of Bubble Continuous Positive Airway Pressure in an In Vitro ModelTsyr-Yuh Ho0Shan-Fu Ou1Shih-Hui Huang2Chi-Ning Lee3Luo-Ping Ger4Kai-Sheng Hsieh5Hui-Ying Cheng6Wei Yang Lee7Ken-Pen Weng8Division of Pediatrics, Zuoying Armed Forces General Hospital, Kaohsiung, TaiwanDivision of Pediatrics, Zuoying Armed Forces General Hospital, Kaohsiung, TaiwanDepartment of Nursing, Fooying University, Kaohsiung County, TaiwanDivision of Pediatrics, Zuoying Armed Forces General Hospital, Kaohsiung, TaiwanDepartment of Pediatrics and Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, National Yang-Ming University, Taipei, TaiwanDepartment of Pediatrics and Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, National Yang-Ming University, Taipei, TaiwanDepartment of Nursing, Zuoying Armed Forces General Hospital, Kaohsiung, TaiwanDepartment of Pediatrics, Kaohsiung Municipal United Hospital, Kaohsiung, TaiwanDivision of Pediatrics, Zuoying Armed Forces General Hospital, Kaohsiung, TaiwanThere has been concern over the effect of vigorous bubbling on the delivery pressure during the operation of the bubble nasal continuous positive airway pressure (CPAP) system. We investigated the relationship between intra-tubing pressure changes and flow rates in a closed bubble CPAP system in vitro. Methods: Using an experimental (in vitro) model, the distal connecting tube of the CPAP system was immersed under the water seal to a depth of 5 cm. Sixteen different flow rates, ranging from 2 L/min to 20 L/min, were tested. The procedure was repeated 10 times at each flow rate, and the intra-tubing pressure was recorded. Results: The intra-tubing pressure within the model increased as the air flow rates were adjusted from 2 L/min to 20 L/min. The relationship was represented by the following equation, pressure (cmH2O) = 5.37 + 0.15 × flow rate (L/min) (R2 = 0.826, p < 0.001). Conclusion: These results demonstrated that the intra-tubing pressure in a bubble CPAP system was highly correlated with flow rate in vitro.http://www.sciencedirect.com/science/article/pii/S1875957210600411bubble CPAPflowpressure
spellingShingle Tsyr-Yuh Ho
Shan-Fu Ou
Shih-Hui Huang
Chi-Ning Lee
Luo-Ping Ger
Kai-Sheng Hsieh
Hui-Ying Cheng
Wei Yang Lee
Ken-Pen Weng
Effects of Flow Rate on Delivery of Bubble Continuous Positive Airway Pressure in an In Vitro Model
Pediatrics and Neonatology
bubble CPAP
flow
pressure
title Effects of Flow Rate on Delivery of Bubble Continuous Positive Airway Pressure in an In Vitro Model
title_full Effects of Flow Rate on Delivery of Bubble Continuous Positive Airway Pressure in an In Vitro Model
title_fullStr Effects of Flow Rate on Delivery of Bubble Continuous Positive Airway Pressure in an In Vitro Model
title_full_unstemmed Effects of Flow Rate on Delivery of Bubble Continuous Positive Airway Pressure in an In Vitro Model
title_short Effects of Flow Rate on Delivery of Bubble Continuous Positive Airway Pressure in an In Vitro Model
title_sort effects of flow rate on delivery of bubble continuous positive airway pressure in an in vitro model
topic bubble CPAP
flow
pressure
url http://www.sciencedirect.com/science/article/pii/S1875957210600411
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