Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (DUSP3) Phosphatase
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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American Chemical Society
2025-01-01
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| Series: | ACS Omega |
| Online Access: | https://doi.org/10.1021/acsomega.4c10321 |
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| author | Jiaqian Wu Marek R. Baranowski Alexander E. Aleshin Eta A. Isiorho Lester J. Lambert Laurent J. S. De Backer Ye Na Han Ranajit Das Douglas J. Sheffler Andrey A. Bobkov Alexis M. Lemberikman Daniel A. Keedy Nicholas D. P. Cosford Lutz Tautz |
| author_facet | Jiaqian Wu Marek R. Baranowski Alexander E. Aleshin Eta A. Isiorho Lester J. Lambert Laurent J. S. De Backer Ye Na Han Ranajit Das Douglas J. Sheffler Andrey A. Bobkov Alexis M. Lemberikman Daniel A. Keedy Nicholas D. P. Cosford Lutz Tautz |
| author_sort | Jiaqian Wu |
| collection | DOAJ |
| format | Article |
| id | doaj-art-8a03765957f74c1e9e006fac7461bcf1 |
| institution | Kabale University |
| issn | 2470-1343 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | ACS Omega |
| spelling | doaj-art-8a03765957f74c1e9e006fac7461bcf12025-02-11T09:15:49ZengAmerican Chemical SocietyACS Omega2470-13432025-01-011054912492610.1021/acsomega.4c10321Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (DUSP3) PhosphataseJiaqian Wu0Marek R. Baranowski1Alexander E. Aleshin2Eta A. Isiorho3Lester J. Lambert4Laurent J. S. De Backer5Ye Na Han6Ranajit Das7Douglas J. Sheffler8Andrey A. Bobkov9Alexis M. Lemberikman10Daniel A. Keedy11Nicholas D. P. Cosford12Lutz Tautz13Cancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United StatesCancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United StatesCancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United StatesStructural Biology Initiative, CUNY Advanced Science Research Center, New York, New York, United StatesCancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United StatesCancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United StatesCancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United StatesCancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United StatesCancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United StatesCancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United StatesStructural Biology Initiative, CUNY Advanced Science Research Center, New York, New York, United StatesStructural Biology Initiative, CUNY Advanced Science Research Center, New York, New York, United StatesCancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United StatesCancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United Stateshttps://doi.org/10.1021/acsomega.4c10321 |
| spellingShingle | Jiaqian Wu Marek R. Baranowski Alexander E. Aleshin Eta A. Isiorho Lester J. Lambert Laurent J. S. De Backer Ye Na Han Ranajit Das Douglas J. Sheffler Andrey A. Bobkov Alexis M. Lemberikman Daniel A. Keedy Nicholas D. P. Cosford Lutz Tautz Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (DUSP3) Phosphatase ACS Omega |
| title | Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (DUSP3) Phosphatase |
| title_full | Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (DUSP3) Phosphatase |
| title_fullStr | Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (DUSP3) Phosphatase |
| title_full_unstemmed | Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (DUSP3) Phosphatase |
| title_short | Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (DUSP3) Phosphatase |
| title_sort | fragment screening identifies novel allosteric binders and binding sites in the vhr dusp3 phosphatase |
| url | https://doi.org/10.1021/acsomega.4c10321 |
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