Translation of bi-directional transcripts enhances MHC-I peptide diversity
Antisense transcripts play an important role in generating regulatory non-coding RNAs but whether these transcripts are also translated to generate functional peptides remains poorly understood. In this study, RNA sequencing and six-frame database generation were combined with mass spectrometry anal...
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| Main Authors: | Filip Zavadil, Tomas Henek, Justine Habault, René Chemali, Maria Camila Tovar-Fernandez, Chrysoula Daskalogianni, Laurence Malbert-Colas, Lixiao Wang, Sivakumar Vadivel Gnanasundram, Borek Vojtesek, Lenka Hernychova, Sebastien Apcher, Robin Fahraeus |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1554561/full |
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