Newborn blood pressure dynamics during immediate postnatal transition - a retrospective analysis
Abstract Background The transition from intrauterine to extrauterine life presents challenges for neonates, who are at increased risk of cardio-respiratory instability. Although electrocardiogram monitoring is recommended for neonatal resuscitation after birth, its ability to assess cardiovascular f...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
|
| Series: | Italian Journal of Pediatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13052-025-02001-y |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850268960583319552 |
|---|---|
| author | Daniel Pfurtscheller Christoph Schlatzer Nina Höller Bernhard Schwaberger Lukas P. Mileder Nariae Baik-Schneditz Gerhard Pichler |
| author_facet | Daniel Pfurtscheller Christoph Schlatzer Nina Höller Bernhard Schwaberger Lukas P. Mileder Nariae Baik-Schneditz Gerhard Pichler |
| author_sort | Daniel Pfurtscheller |
| collection | DOAJ |
| description | Abstract Background The transition from intrauterine to extrauterine life presents challenges for neonates, who are at increased risk of cardio-respiratory instability. Although electrocardiogram monitoring is recommended for neonatal resuscitation after birth, its ability to assess cardiovascular function is limited. Measuring arterial blood pressure (ABP) is feasible in neonates during the immediate transition period, though its interpretation is complex. This study analyses ABP values during the immediate transition in preterm neonates. Methods Data from neonates born at the Medical University of Graz between 2009 and 2023 were analysed. All preterm neonates who survived without intraventricular haemorrhage grade II or higher, and who had ABP measured non-invasively at 15 min after birth, were eligible for inclusion. Statistical analyses were employed to evaluate ABP values for each gestational week, ranging from 23 to 36 weeks of gestation. Results Out of 305 eligible neonates, 267 preterm neonates met the inclusion criteria. The median (IQR) systolic ABP ranged from 46 (43–51) to 64 (56–68) mmHg showing a gradual increase with advancing gestational age. The mean ABP ranged from 30 (27–36) to 45 (37–47) mmHg, also exhibiting a gradual increase with higher gestational age. Similarly, the diastolic ABP ranged from 22 (19–29) to 34 (29–41) mmHg, again showing a gradual increase with advancing gestational age. Conclusion The findings indicate that ABP values during the immediate transition may be higher than those described after immediate transition in large cohort studies. Moreover, the gradual increase in ABP in preterm neonates with advancing gestational age underscores the necessity for tailored approaches to neonatal cardiovascular management during immediate transition. |
| format | Article |
| id | doaj-art-89ddc0bea00e40abbae6e9e4ef14ed21 |
| institution | OA Journals |
| issn | 1824-7288 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Italian Journal of Pediatrics |
| spelling | doaj-art-89ddc0bea00e40abbae6e9e4ef14ed212025-08-20T01:53:19ZengBMCItalian Journal of Pediatrics1824-72882025-05-015111910.1186/s13052-025-02001-yNewborn blood pressure dynamics during immediate postnatal transition - a retrospective analysisDaniel Pfurtscheller0Christoph Schlatzer1Nina Höller2Bernhard Schwaberger3Lukas P. Mileder4Nariae Baik-Schneditz5Gerhard Pichler6Research Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of GrazResearch Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of GrazResearch Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of GrazResearch Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of GrazResearch Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of GrazResearch Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of GrazResearch Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of GrazAbstract Background The transition from intrauterine to extrauterine life presents challenges for neonates, who are at increased risk of cardio-respiratory instability. Although electrocardiogram monitoring is recommended for neonatal resuscitation after birth, its ability to assess cardiovascular function is limited. Measuring arterial blood pressure (ABP) is feasible in neonates during the immediate transition period, though its interpretation is complex. This study analyses ABP values during the immediate transition in preterm neonates. Methods Data from neonates born at the Medical University of Graz between 2009 and 2023 were analysed. All preterm neonates who survived without intraventricular haemorrhage grade II or higher, and who had ABP measured non-invasively at 15 min after birth, were eligible for inclusion. Statistical analyses were employed to evaluate ABP values for each gestational week, ranging from 23 to 36 weeks of gestation. Results Out of 305 eligible neonates, 267 preterm neonates met the inclusion criteria. The median (IQR) systolic ABP ranged from 46 (43–51) to 64 (56–68) mmHg showing a gradual increase with advancing gestational age. The mean ABP ranged from 30 (27–36) to 45 (37–47) mmHg, also exhibiting a gradual increase with higher gestational age. Similarly, the diastolic ABP ranged from 22 (19–29) to 34 (29–41) mmHg, again showing a gradual increase with advancing gestational age. Conclusion The findings indicate that ABP values during the immediate transition may be higher than those described after immediate transition in large cohort studies. Moreover, the gradual increase in ABP in preterm neonates with advancing gestational age underscores the necessity for tailored approaches to neonatal cardiovascular management during immediate transition.https://doi.org/10.1186/s13052-025-02001-yBlood pressure 1Neonates 2Immediate transition 3Extreme preterm 4Hemodynamics 5 |
| spellingShingle | Daniel Pfurtscheller Christoph Schlatzer Nina Höller Bernhard Schwaberger Lukas P. Mileder Nariae Baik-Schneditz Gerhard Pichler Newborn blood pressure dynamics during immediate postnatal transition - a retrospective analysis Italian Journal of Pediatrics Blood pressure 1 Neonates 2 Immediate transition 3 Extreme preterm 4 Hemodynamics 5 |
| title | Newborn blood pressure dynamics during immediate postnatal transition - a retrospective analysis |
| title_full | Newborn blood pressure dynamics during immediate postnatal transition - a retrospective analysis |
| title_fullStr | Newborn blood pressure dynamics during immediate postnatal transition - a retrospective analysis |
| title_full_unstemmed | Newborn blood pressure dynamics during immediate postnatal transition - a retrospective analysis |
| title_short | Newborn blood pressure dynamics during immediate postnatal transition - a retrospective analysis |
| title_sort | newborn blood pressure dynamics during immediate postnatal transition a retrospective analysis |
| topic | Blood pressure 1 Neonates 2 Immediate transition 3 Extreme preterm 4 Hemodynamics 5 |
| url | https://doi.org/10.1186/s13052-025-02001-y |
| work_keys_str_mv | AT danielpfurtscheller newbornbloodpressuredynamicsduringimmediatepostnataltransitionaretrospectiveanalysis AT christophschlatzer newbornbloodpressuredynamicsduringimmediatepostnataltransitionaretrospectiveanalysis AT ninaholler newbornbloodpressuredynamicsduringimmediatepostnataltransitionaretrospectiveanalysis AT bernhardschwaberger newbornbloodpressuredynamicsduringimmediatepostnataltransitionaretrospectiveanalysis AT lukaspmileder newbornbloodpressuredynamicsduringimmediatepostnataltransitionaretrospectiveanalysis AT nariaebaikschneditz newbornbloodpressuredynamicsduringimmediatepostnataltransitionaretrospectiveanalysis AT gerhardpichler newbornbloodpressuredynamicsduringimmediatepostnataltransitionaretrospectiveanalysis |