Transjugular Portosystemic Shunting in Refractory Cirrhotic Ascites
Aim. Improvement of refractory ascites (RA) outcomes in underlying cirrhotic portal hypertension (PH) through optimising the transjugular intrahepatic portosystemic shunting (TIPS) procedure among therapy measures.Materials and methods. The survey included 107 patients with RA admitted to portal hyp...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2021-04-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/542 |
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| author | Yu. V. Khoronko M. A. Kozyrevskiy A. V. Dmitriev A. A. Volokhova G. Yu. Spiridenko K. R. Bogomolova |
| author_facet | Yu. V. Khoronko M. A. Kozyrevskiy A. V. Dmitriev A. A. Volokhova G. Yu. Spiridenko K. R. Bogomolova |
| author_sort | Yu. V. Khoronko |
| collection | DOAJ |
| description | Aim. Improvement of refractory ascites (RA) outcomes in underlying cirrhotic portal hypertension (PH) through optimising the transjugular intrahepatic portosystemic shunting (TIPS) procedure among therapy measures.Materials and methods. The survey included 107 patients with RA admitted to portal hypertension units of the Rostov State Medical University Surgical Clinic during 2007—2020. The patients were randomly assigned to two cohorts similar by gender, age, cirrhosis aetiology and condition severity. The control cohort had conventional paracentesis and albumin infusion. In cohort 2, 57 patients had minimally invasive endovascular TIPS surgery in a recommended setting.Results. TIPS eliminated PH in all 57 patients of cohort 2. Cohort 1 was reported with progressive esophagogastric varices (EGV), their enlargement in 37 and rupture in 11 patients during the first 12 months. Cohort 2 revealed the grade 3—2 and 2—1 EGV reduction in 24 (41.1%) patients with shunt surgery and in 39 (68.4%) patients in one year. Esophagogastric variceal bleeding (EGVB) developed in 9 patients in cohort 1, with 7 lethal outcomes. No variceal bleeding was observed in cohort 2, with 7 patients having the portosystemic shunt dysfunction.Conclusion. The TIPS procedure is justified in cirrhotic PH patients with RA for reducing the mortality rate in a one year follow-up. |
| format | Article |
| id | doaj-art-89cdcb7305294e8d8f2945411c411bd5 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2021-04-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-89cdcb7305294e8d8f2945411c411bd52025-02-10T16:14:36ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732021-04-01311394610.22416/1382-4376-2021-31-1-39-46415Transjugular Portosystemic Shunting in Refractory Cirrhotic AscitesYu. V. Khoronko0M. A. Kozyrevskiy1A. V. Dmitriev2A. A. Volokhova3G. Yu. Spiridenko4K. R. Bogomolova5Rostov State Medical UniversityRostov State Medical UniversityRostov State Medical UniversityRostov State Medical UniversityRostov State Medical UniversityRostov State Medical UniversityAim. Improvement of refractory ascites (RA) outcomes in underlying cirrhotic portal hypertension (PH) through optimising the transjugular intrahepatic portosystemic shunting (TIPS) procedure among therapy measures.Materials and methods. The survey included 107 patients with RA admitted to portal hypertension units of the Rostov State Medical University Surgical Clinic during 2007—2020. The patients were randomly assigned to two cohorts similar by gender, age, cirrhosis aetiology and condition severity. The control cohort had conventional paracentesis and albumin infusion. In cohort 2, 57 patients had minimally invasive endovascular TIPS surgery in a recommended setting.Results. TIPS eliminated PH in all 57 patients of cohort 2. Cohort 1 was reported with progressive esophagogastric varices (EGV), their enlargement in 37 and rupture in 11 patients during the first 12 months. Cohort 2 revealed the grade 3—2 and 2—1 EGV reduction in 24 (41.1%) patients with shunt surgery and in 39 (68.4%) patients in one year. Esophagogastric variceal bleeding (EGVB) developed in 9 patients in cohort 1, with 7 lethal outcomes. No variceal bleeding was observed in cohort 2, with 7 patients having the portosystemic shunt dysfunction.Conclusion. The TIPS procedure is justified in cirrhotic PH patients with RA for reducing the mortality rate in a one year follow-up.https://www.gastro-j.ru/jour/article/view/542portal hypertensiontipsrefractory ascitesliver cirrhosisesophagogastric varicesbleedinghepatorenal syndrome |
| spellingShingle | Yu. V. Khoronko M. A. Kozyrevskiy A. V. Dmitriev A. A. Volokhova G. Yu. Spiridenko K. R. Bogomolova Transjugular Portosystemic Shunting in Refractory Cirrhotic Ascites Российский журнал гастроэнтерологии, гепатологии, колопроктологии portal hypertension tips refractory ascites liver cirrhosis esophagogastric varices bleeding hepatorenal syndrome |
| title | Transjugular Portosystemic Shunting in Refractory Cirrhotic Ascites |
| title_full | Transjugular Portosystemic Shunting in Refractory Cirrhotic Ascites |
| title_fullStr | Transjugular Portosystemic Shunting in Refractory Cirrhotic Ascites |
| title_full_unstemmed | Transjugular Portosystemic Shunting in Refractory Cirrhotic Ascites |
| title_short | Transjugular Portosystemic Shunting in Refractory Cirrhotic Ascites |
| title_sort | transjugular portosystemic shunting in refractory cirrhotic ascites |
| topic | portal hypertension tips refractory ascites liver cirrhosis esophagogastric varices bleeding hepatorenal syndrome |
| url | https://www.gastro-j.ru/jour/article/view/542 |
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