ASSESSMENT OF CANDIDA ALBICANS ADHERENCE TO PARTIAL REMOVABLE DENTURE FRAMEWORK SURFACES
Aim of the study This study aimed to evaluate the adhesion of Candida albicans to cobalt-chromium-molybdenum (Co-Cr-Mo) removable partial denture (RPD) frameworks subjected to different surface treatments, and to assess the antifungal susceptibility of the isolated strains. Materials and Methods A t...
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| Format: | Article |
| Language: | English |
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Romanian Society of Oral Rehabilitation
2025-06-01
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| Series: | Romanian Journal of Oral Rehabilitation |
| Online Access: | https://rjor.ro/assessment-of-candida-albicans-adherence-to-partial-removable-denture-framework-surfaces/ |
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| author | Elena-Raluca Baciu Sorana Nicoleta Roșu Iulian-Costin Lupu Alice Murariu Norina Consuela Forna |
| author_facet | Elena-Raluca Baciu Sorana Nicoleta Roșu Iulian-Costin Lupu Alice Murariu Norina Consuela Forna |
| author_sort | Elena-Raluca Baciu |
| collection | DOAJ |
| description | Aim of the study This study aimed to evaluate the adhesion of Candida albicans to cobalt-chromium-molybdenum (Co-Cr-Mo) removable partial denture (RPD) frameworks subjected to different surface treatments, and to assess the antifungal susceptibility of the isolated strains. Materials and Methods A total of 52 RPDs were fabricated for 34 patients and divided into two groups based on surface finishing: mechanical polishing only and combined mechanical-electrolytic polishing. Surface roughness measurements were conducted prior to clinical use. Microbiological samples were collected after patient wear, cultured on CHROMagar Candida medium, and subjected to antifungal susceptibility testing against five antifungal agents. Results RPDs treated with mechanical polishing alone exhibited significantly higher surface roughness compared to those subjected to both mechanical and electrolytic polishing (p < 0.001). Higher surface roughness was associated with increased Candida albicans colonization (p = 0.005). Most Candida albicans strains remained susceptible to standard antifungal agents, although minor resistance to miconazole was observed. Conclusions Surface finishing significantly influences Candida albicans adhesion to Co-Cr-Mo RPD frameworks. Combined mechanical and electrolytic polishing effectively reduces surface roughness and microbial colonization. These findings highlight the importance of optimizing surface treatments to minimize prosthesis-related infections and support better clinical outcomes.
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| format | Article |
| id | doaj-art-89c9c720c3eb4a97a68464d906cf0bb8 |
| institution | Kabale University |
| issn | 2066-7000 2601-4661 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Romanian Society of Oral Rehabilitation |
| record_format | Article |
| series | Romanian Journal of Oral Rehabilitation |
| spelling | doaj-art-89c9c720c3eb4a97a68464d906cf0bb82025-08-20T03:37:02ZengRomanian Society of Oral RehabilitationRomanian Journal of Oral Rehabilitation2066-70002601-46612025-06-0117242042710.62610/RJOR.2025.2.17.37ASSESSMENT OF CANDIDA ALBICANS ADHERENCE TO PARTIAL REMOVABLE DENTURE FRAMEWORK SURFACESElena-Raluca Baciu0Sorana Nicoleta Roșu1Iulian-Costin Lupu2Alice Murariu3Norina Consuela Forna4”Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania, Faculty of Dental Medicine, Department of Implantology, Removable Dentures, Dental Technology”Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania, Faculty of Dental Medicine, Department of Surgicals”Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania, Faculty of Dental Medicine, Department of Implantology, Removable Dentures, Dental Technology”Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania, Faculty of Dental Medicine, Department of Surgicals”Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania, Faculty of Dental Medicine, Department of Implantology, Removable Dentures, Dental TechnologyAim of the study This study aimed to evaluate the adhesion of Candida albicans to cobalt-chromium-molybdenum (Co-Cr-Mo) removable partial denture (RPD) frameworks subjected to different surface treatments, and to assess the antifungal susceptibility of the isolated strains. Materials and Methods A total of 52 RPDs were fabricated for 34 patients and divided into two groups based on surface finishing: mechanical polishing only and combined mechanical-electrolytic polishing. Surface roughness measurements were conducted prior to clinical use. Microbiological samples were collected after patient wear, cultured on CHROMagar Candida medium, and subjected to antifungal susceptibility testing against five antifungal agents. Results RPDs treated with mechanical polishing alone exhibited significantly higher surface roughness compared to those subjected to both mechanical and electrolytic polishing (p < 0.001). Higher surface roughness was associated with increased Candida albicans colonization (p = 0.005). Most Candida albicans strains remained susceptible to standard antifungal agents, although minor resistance to miconazole was observed. Conclusions Surface finishing significantly influences Candida albicans adhesion to Co-Cr-Mo RPD frameworks. Combined mechanical and electrolytic polishing effectively reduces surface roughness and microbial colonization. These findings highlight the importance of optimizing surface treatments to minimize prosthesis-related infections and support better clinical outcomes. https://rjor.ro/assessment-of-candida-albicans-adherence-to-partial-removable-denture-framework-surfaces/ |
| spellingShingle | Elena-Raluca Baciu Sorana Nicoleta Roșu Iulian-Costin Lupu Alice Murariu Norina Consuela Forna ASSESSMENT OF CANDIDA ALBICANS ADHERENCE TO PARTIAL REMOVABLE DENTURE FRAMEWORK SURFACES Romanian Journal of Oral Rehabilitation |
| title | ASSESSMENT OF CANDIDA ALBICANS ADHERENCE TO PARTIAL REMOVABLE DENTURE FRAMEWORK SURFACES |
| title_full | ASSESSMENT OF CANDIDA ALBICANS ADHERENCE TO PARTIAL REMOVABLE DENTURE FRAMEWORK SURFACES |
| title_fullStr | ASSESSMENT OF CANDIDA ALBICANS ADHERENCE TO PARTIAL REMOVABLE DENTURE FRAMEWORK SURFACES |
| title_full_unstemmed | ASSESSMENT OF CANDIDA ALBICANS ADHERENCE TO PARTIAL REMOVABLE DENTURE FRAMEWORK SURFACES |
| title_short | ASSESSMENT OF CANDIDA ALBICANS ADHERENCE TO PARTIAL REMOVABLE DENTURE FRAMEWORK SURFACES |
| title_sort | assessment of candida albicans adherence to partial removable denture framework surfaces |
| url | https://rjor.ro/assessment-of-candida-albicans-adherence-to-partial-removable-denture-framework-surfaces/ |
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